3rd International Clinical Trials Methodology Conference

The madness of HIV prevention trials

S McCormack

Trials 2015 16(Suppl 2):I1

Published on: 16 November 2015

Discussion session: biomarker trials

Trials 2015 16(Suppl 2):I2

Published on: 16 November 2015

Science in a crisis: conducting clinical trials in an emergency

P Horby

Trials 2015 16(Suppl 2):I3

Published on: 16 November 2015

Good practice principles for sharing individual participant data from publicly funded clinical trials

Catrin Tudur Smith, Carolyn Hopkins, Matt Sydes, Kerry Woolfall, Mike Clarke, Gordon Murray and Paula Williamson

Trials 2015 16(Suppl 2):O1

Published on: 16 November 2015

Reading or listening to review summaries - which method will produce greater understanding of the key outcomes in a cochrane review?

Lisa Maguire, Mike Clarke and Mark Tully

Trials 2015 16(Suppl 2):O2

Published on: 16 November 2015

How are systematic reviews used in the planning and design of health technology assessment funded trials?

Sheetal Bhurke, Andrew Cook, Anna Tallant, Amanda Young, Elaine Williams and James Raftery

Trials 2015 16(Suppl 2):O3

Published on: 16 November 2015

The value of evidence synthesis in randomised controlled trial (RCT) design, conduct and analysis: MRC clinical trials unit (CTU) at UCL experience

Jayne F Tierney, Sarah Burdett, Claire Vale, Larysa Rydzewska, Matthew R Sydes, Ruth E Langley, Richard S Kaplan and Mahesh KB Parmar

Trials 2015 16(Suppl 2):O4

Published on: 16 November 2015

Methods for selecting health concepts and domains from in-depth qualitative interviews for the development of patient reported outcome measures (PROMS): a case study

Jane Blazeby, Leila Rooshenas, Rhiannon Macefield, Daisy Townsend and Tom Milne

Trials 2015 16(Suppl 2):O5

Published on: 16 November 2015

Development of a single, practical measure of surgical site infection (SSI) for patient self-report and observer completion: a novel method of questionnaire design

Rhiannon Macefield, Alex Nicholson, Tom Milne, Thomas Pinkney, Melanie Calvert, Kerry Avery, Barnaby Reeves and Jane Blazeby

Trials 2015 16(Suppl 2):O6

Published on: 16 November 2015

Understanding patterns of adverse events after surgery and their impact on recovery

Rachel L Nash, Barnaby C Reeves, Gianni D Angelini and Chris A Rogers

Trials 2015 16(Suppl 2):O7

Published on: 16 November 2015

Ongoing validation of health-related quality of life instruments

Kim Cocks and Puvan Tharmanathan

Trials 2015 16(Suppl 2):O8

Published on: 16 November 2015

Trials within trials of interventions to improve recruitment and retention: the experience of York Trials Unit

David Torgerson and Caroline Fairhurst

Trials 2015 16(Suppl 2):O9

Published on: 16 November 2015

Assessing the effectiveness of a ‘site visit’ on recruitment rates in a multicentre randomised trial: SWAT-1

Valerie Smith, Mike Clarke, Cecily Begley and Declan Devane

Trials 2015 16(Suppl 2):O10

Published on: 16 November 2015

Scoop pen sub-study-a ‘trial within a trial’ of enclosing a pen in questionnaire mailings to increase response rate

Caroline Fairhurst, Kerry Bell, Laura Clark, Natasha Mitchell, Elizabeth Lenaghan, Jeanette Blacklock, Lee Shepstone and David Torgerson

Trials 2015 16(Suppl 2):O11

Published on: 16 November 2015

Developing guidelines for reporting embedded recruitment trials

Vichithranie W Madurasinghe, Sandra Eldridge and Gordon Forbes

Trials 2015 16(Suppl 2):O12

Published on: 16 November 2015

Dose transition pathways: a design, analysis and operational tool for dose-finding trials using model-based designs

Christina Yap, Lucinda Billingham, Charles Craddock and John O'Quigley

Trials 2015 16(Suppl 2):O13

Published on: 16 November 2015

Conducting a randomised trial during an influenza pandemic: an example of a trial set up and ‘hibernated’ ready to activate and recruit within 4 weeks

Clare Brittain, Garry Meakin, Margo Childs, Lelia Duley and Wei Shen Lim

Trials 2015 16(Suppl 2):O14

Published on: 16 November 2015

Using the UK renal registry for a clinical trial in dialysis patients: the example of SIMPLIFIED

Simon Bond, Rupert Payne, Edward Wilson, Afzal Chowdry, Fergus Caskey, David Wheeler and Thomas Hiemstra

Trials 2015 16(Suppl 2):O15

Published on: 16 November 2015

The design of a multi-arm multi-stage (MAMS) phase III randomised controlled trial comparing alternative regimens for escalating (COMPARE) treatment of intermediate and high-risk oropharyngeal cancer with reflections on the complications of introducing a new experimental ARM

Piers Gaunt, Hisham Mehanna and Christina Yap

Trials 2015 16(Suppl 2):O16

Published on: 16 November 2015

Progression from an internal pilot of a main trial including adaptation from a two to three group study - straightforward to do?

Danielle Edwards, Graziella Mazza, Rachael Heys, Caroline Wilson, Jane Blazeby and Chris Rogers

Trials 2015 16(Suppl 2):O17

Published on: 16 November 2015