The trial was terminated early based on the results of the interim efficacy analysis. FCM-MiniR was not expected to be cost-effective over a lifetime horizon, producing an average lifetime cost saving of £7,708 and health loss of -0.67 QALYs. The VOIA, however, suggested a high value of further research due to uncertainty around key parameters. Whilst the CEA results support the interim efficacy findings, the VOIA results highlight the cost of trial termination in terms of potential population net health loss (1,050 QALYs) by foregoing the opportunity to collect additional data.