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Trials

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Featured article: Can routine data be used to support cancer clinical trials?

When investigating whether a treatment works, randomized controlled trials are the gold standard but require huge amounts of resource. Here, Lucy Suzanne Kilburn, The Institute of Cancer Research, and colleagues assessed the potential for routine data to inform cancer trials, using the National Cancer Data Repository as a test source, and data available from the TACT trial for validation.

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  1. Content type: Review

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    Authors: Barbara Farrell, Sara Kenyon and Haleema Shakur

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Trials is published continuously online-only. We encourage you to sign up to receive free email alerts to keep up to date with all of the latest articles by registering here.

Aims and scope

Trials encompasses all aspects of the performance and findings of randomized controlled trials in health. Trials encourages full and transparent reporting of all research.  We publish articles on general trial methodology as well as protocols, commentaries and traditional results papers - regardless of outcome or significance of findings.

Article collections

Thematic series
Ten years of Trials

Thematic series
Stepped wedge randomized controlled trials
Edited by Prof David Torgerson

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Thank you to our peer reviewers

The editors and staff of Trials would like to warmly thank our peer reviewers whose comments have helped to shape the journal.

Latest Tweets

Call for papers: Building capacity for evidence informed trial management

We are pleased to announce that Trials is accepting submissions for a new thematic series aimed at building the evidence base for trial management. Co-edited by Dr Roberta Littleford (University of Dundee, UK) and Prof Shaun Treweek (University of Aberdeen, UK), this series will include articles that report on what is currently known about effective trial management processes and how to make trial management more evidence-informed.

Doug Altman

About the Editors

Doug Altman, Editor-in-Chief

Doug Altman graduated in statistics from the University of Bath and has worked for the Medical Research Council as a statistical consultant in a wide variety of medical areas. In 1988 he became head of the newly formed Medical Statistics Laboratory (now Medical Statistics Group) at ICRF (now Cancer Research UK), and in 1995 also became founding director of the Centre for Statistics in Medicine in Oxford. In 1997, Professor Altman received the Bradford Hill Medal for his contributions to medical statistics and a DSc from the University of London, and in 1998 was made Professor of Statistics in Medicine by the University of Oxford. His varied research interests include the use and abuse of statistics in medical research, studies of prognosis, regression modelling, systematic reviews and meta-analysis, randomised trials, and studies of medical measurement.

Jeremy Grimshaw

Jeremy Grimshaw, Editor-in-Chief

Jeremy Grimshaw is a Senior Scientist in the Clinical Epidemiology Program at the Ottawa Health Research Institute and Professor of Medicine, University of Ottawa. He holds a Tier 1 Canadian Research Chair in health knowledge transfer and uptake. Professor Grimshaw’s research interests are in implementation and knowledge translation, quality improvement, complex interventions, systematic reviews, cluster randomized trials, quasi-experimental studies and behavioral theories (and their application to professional behavior).

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Tianjing Li, Editor-in-Chief

Tianjing Li is an Associate Professor in the Department of Epidemiology at Johns Hopkins Bloomberg School of Public Health (JHBSPH). Dr Li was trained as a physician and subsequently earned her PhD in Epidemiology (Clinical Trials concentration) and MHS in Biostatistics from JHBSPH. The primary goal of Dr Li's research is to develop, evaluate, and disseminate efficient methods for comparing healthcare interventions and to provide trustworthy evidence for decision making. Her core research interests include methodologies for randomized controlled trials, systematic reviews, network meta-analysis, comparative effectiveness research, and patient-centered outcomes research. Dr Li serves as the Associate Director for Cochrane United States and the Director for Research for Cochrane Eyes and Vision US Project.

Celebrating Trials' 10th anniversary

2016 marked the 10th anniversary of Trials and to coincide with publication of our 3000th article, we put together a page to celebrate the great milestones of the journal, including a timeline, opinions from those in the field, links to our most popular articles, and more.

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2016 Journal Metrics

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