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  1. Systemic glucocorticoids are effective for the management of chronic obstructive pulmonary disease (COPD) exacerbation but have serious adverse effects. Traditional Chinese medicine (TCM) can bring additional ...

    Authors: Qing Kong, Shuming Mo, Wenqian Wang, Zihui Tang, Ying Wei, Yijie Du, Baojun Liu, Lingwen Kong, Yubao Lv and Jingcheng Dong

    Citation: Trials 2020 21:760

    Content type: Study protocol

    Published on:

  2. The prevalence of obesity in women continues to rise and pregnancy is a high-risk time for excessive weight gain. The period after childbirth represents an opportunity to offer women support to manage their we...

    Authors: A. J. Daley, K. Jolly, H. Bensoussane, N. Ives, S. A. Jebb, S. Tearne, S. M. Greenfield, L. Yardley, P. Little, N. Tyldesley-Marshall, R. V. Pritchett, E. Frew and H. M. Parretti

    Citation: Trials 2020 21:757

    Content type: Research

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  3. Globally, 45% of under-five deaths are either directly or indirectly attributable to malnutrition, and most of these deaths are in low- and middle-income countries (LMICs). Children are particularly vulnerable...

    Authors: Ameer Muhammad, Yasir Shafiq, Muhammad Imran Nisar, Benazir Baloch, Amna Tanweer Yazdani, Nida Yazdani and Fyezah Jehan

    Citation: Trials 2020 21:756

    Content type: Study protocol

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  4. Rheumatoid arthritis (RA) is one of the leading chronic inflammatory rheumatism. First-line therapy with synthetic disease-modifying antirheumatic drugs (sDMARD) is insufficiently effective in 40% of cases and...

    Authors: Dalifer Freites-Núñez, Athan Baillet, Luis Rodriguez-Rodriguez, Minh Vu Chuong Nguyen, Isidoro Gonzalez, Jose Luis Pablos, Alejandro Balsa, Monica Vazquez, Philippe Gaudin and Benjamín Fernandez-Gutierrez

    Citation: Trials 2020 21:755

    Content type: Study protocol

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  5. To evaluate the effect of the combination of hydroxychloroquine (HCQ) and standard personal protective equipment (PPE) compared to the use of standard personal protective equipment alone on the proportion of l...

    Authors: Bharath Kumar Tirupakuzhi Vijayaraghavan, Vivekanand Jha, Dorrilyn Rajbhandari, Sheila Nainan Myatra, Oommen John, Arpita Ghosh, Abhinav Bassi, Sumaiya Arfin, Mallikarjuna Kunigari, Rohina Joshi, Lachlan Donaldson, Naomi Hammond and Balasubramanian Venkatesh

    Citation: Trials 2020 21:754

    Content type: Letter

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  6. Post-stroke cognitive impairment (PSCI) is a series of syndromes that meet the diagnostic criteria for cognitive impairment that appear after a stroke. The treatment of PSCI with oral drugs alone is not ideal ...

    Authors: Ruijia Liu, Xudong Yu, Jisheng Wang, Ye Liu, Bowen Liu, Xinwei Li, Yue Wang, Tianyu Cao and Hongwei Yuan

    Citation: Trials 2020 21:753

    Content type: Study protocol

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  7. The hemodialysis setting is suitable for trials that use cluster randomization, where intact groups of individuals are randomized. However, cluster randomized trials (CRTs) are complicated in their design, ana...

    Authors: Ahmed A. Al-Jaishi, Kelly Carroll, Cory E. Goldstein, Stephanie N. Dixon, Amit X. Garg, Stuart G. Nicholls, Jeremy M. Grimshaw, Charles Weijer, Jamie Brehaut, Lehana Thabane, P. J. Devereaux and Monica Taljaard

    Citation: Trials 2020 21:752

    Content type: Review

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  8. In December 2019, pneumonia associated with the 2019 novel coronavirus (COVID-19) emerged in Wuhan, China. The number of cases has increased rapidly. Patients with severe disease have a poor prognosis, and the...

    Authors: Shuaipan Zhang, Qingguang Zhu, Chao Zhan, Wei Cheng, Xiao Mingfang, Min Fang and Lei Fang

    Citation: Trials 2020 21:751

    Content type: Study protocol

    Published on:

  9. The prevalence of hyperlipidemia continues to increase due to aging and lifestyle changes. Statins are currently used as the first choice for treating hyperlipidemia, but are limited by adverse reactions. Hwan...

    Authors: Boram Lee, Kyungsun Han, Hyo-Ju Park, Ae-Ran Kim, O-Jin Kwon, Changsop Yang and Chung-Sik Cho

    Citation: Trials 2020 21:750

    Content type: Study protocol

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  10. Breast cancer patients are at a four-fold increased risk of developing a venous thromboembolism (VTE), a major cause of death in this group. Conversely, coagulation factors promote tumour growth and metastasis...

    Authors: John Castle, Emma Blower, Nigel J. Bundred, James R. Harvey, Jecko Thachil, Andrea Marshall, Karina Cox, Silvia Cicconi, Chris Holcombe, Carlos Palmieri and Cliona C. Kirwan

    Citation: Trials 2020 21:749

    Content type: Study protocol

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  11. The first case of a coronavirus 2019 (COVID-19) infection in a Sri Lankan was reported on March 11, 2020. The situation in Sri Lanka changed with the rapid increase of personnel contracting COVID-19 in a naval...

    Authors: Madunil A. Niriella, Dileepa S. Ediriweera, Arjuna P. De Silva, Ranjan Premarathne, Priyantha Balasooriya, Kaluthanthri D. Duminda, Neelika G. Malavige, Kamani Wanigasuriya, Sarath Lekamwasam, Senanayake A. Kularathne, Sisira Siribaddana, Hithanadura J. de Silva and Saroj Jayasinghe

    Citation: Trials 2020 21:748

    Content type: Study protocol

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  12. Menstrual distress caused by primary dysmenorrhea is associated with physical and psychological symptoms—before, after, and during menstruation. Leventhal’s self-regulation educational model is based on the co...

    Authors: Somayeh Asgari, Zainab Alimoardi, Mohammad Ali Soleimani, Kelly-Ann Allen and Nasim Bahrami

    Citation: Trials 2020 21:747

    Content type: Study protocol

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  13. To investigate the effect of continuous infusion of the potential endothelial cytoprotective agent prostacyclin (Iloprost) 1 ng/kg/min vs. placebo for 72 hours on pulmonary endotheliopathy in mechanically vent...

    Authors: Pär Ingemar Johansson, Morten Bestle, Peter Søe-Jensen, Klaus Tjelle Kristiansen, Jakob Stensballe, Niels Erikstrup Clausen and Anders Perner

    Citation: Trials 2020 21:746

    Content type: Letter

    Published on:

  14. Improving children and young people’s provision for mental health is a current health priority in England. Secondary school teachers have worse mental health outcomes than the general working population, which...

    Authors: Harriet Fisher, Sarah Harding, Sarah Bell, Lauren Copeland, Rhiannon Evans, Jillian Powell, Ricardo Araya, Rona Campbell, Tamsin Ford, David Gunnell, Simon Murphy and Judi Kidger

    Citation: Trials 2020 21:745

    Content type: Research

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  15. Regenerative therapies offer new approaches to improve cardiac function after acute ST-elevation myocardial infarction (STEMI). Previous trials using bone marrow cells, selected stem cell populations, or cardi...

    Authors: Dirk von Lewinski, Joseph B. Selvanayagam, Richard A. Schatz, Bernd Jilma, Jacek Kubica, Thomas J. Povsic, Darrell Nix, Stephan Henauer and Markus Wallner

    Citation: Trials 2020 21:744

    Content type: Study protocol

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  16. The aim of this study is to explore the effectiveness and safety of high dose dexamethasone treatment for Acute Respiratory Distress Syndrome secondary to SARS-Cov-2 pneumonia.

    Authors: Luis Patricio Maskin, Gabriel Leonardo Olarte, Fernando Palizas Jr, Agostina E. Velo, María Fernanda Lurbet, Ignacio Bonelli, Natalio D. Baredes and Pablo Oscar Rodríguez

    Citation: Trials 2020 21:743

    Content type: Letter

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  17. Iron deficiency is common in pregnancy. If left untreated, iron deficiency can lead to iron deficiency anaemia, which is a condition related to maternal and neonatal morbidity. The prevalence of iron deficienc...

    Authors: Veronika Markova, Rebecka Hansen, Lars Lykke Thomsen, Anja Pinborg, Torben Moos and Charlotte Holm

    Citation: Trials 2020 21:742

    Content type: Study protocol

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  18. The purpose of this double-blind, randomised, placebo-controlled, adaptive design trial with frequent interim analyses is to determine if Australian Indigenous children, who receive an additional (third) dose ...

    Authors: Mark A Jones, Todd Graves, Bianca Middleton, James Totterdell, Thomas L Snelling and Julie A Marsh

    Citation: Trials 2020 21:741

    Content type: Update

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  19. Critically ill patients rapidly develop muscle wasting resulting in sarcopenia, long-term disability and higher mortality. Bolus nutrition (30–60 min period), whilst having a similar incidence of aspiration as...

    Authors: Simona Reinhold, Desirée Yeginsoy, Alexa Hollinger, Atanas Todorov, Lionel Tintignac, Michael Sinnreich, Caroline Kiss, Caroline E. Gebhard, Balázs Kovács, Bianca Gysi, Lara Imwinkelried and Martin Siegemund

    Citation: Trials 2020 21:740

    Content type: Study protocol

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  20. Fire needle therapy is a characteristic treatment in traditional Chinese medicine (TCM). An increasing number of studies have indicated that fire needle treatment for psoriasis provides satisfactory results wi...

    Authors: Liu Liu, Yi Lu, Xiao-ning Yan, Su-qing Yang, Li-ping Gong, Ling-e Li, Yi-ding Zhao, Qing-feng Yin, Rui-ping Wang, Yue-peng An, Gang Huang, Jin-fang Zhang, Xiao-ying Sun, Xin Li and Bin Li

    Citation: Trials 2020 21:739

    Content type: Study protocol

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  21. This study aims to determine the protection provided by Shenfu injection (a traditional Chinese medicine) against development of organ dysfunction in critically ill patients with coronavirus disease 2019 (COVI...

    Authors: Zong-Yu Wang, Shou-Zhi Fu, Liang Xu, Shu-Sheng Li, Ke-Jian Qian, Xian-Di He, Guo-Chao Zhu, Liang-Hai Li, Jun Zhang, Wen-Fang Li, Bing-Yu Qin, Chen-Liang Zhou and Peng-Lin Ma

    Citation: Trials 2020 21:738

    Content type: Letter

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  22. The Maternal and Child Health (MCH) handbook is an integrated home-based record (HBR) designed to record in a single document all the information regarding health services provided to a pregnant woman and her ...

    Authors: Olukunmi Omobolanle Balogun, Caroline Kaori Tomo, Keiji Mochida, Masashi Mikami, Henda da Rosa Vasconcelos, Isilda Neves, Hisakazu Hiraoka, Hirotsugu Aiga, Rintaro Mori and Kenji Takehara

    Citation: Trials 2020 21:737

    Content type: Study protocol

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  23. Osteoarthritis (OA) is a health condition sensitive to patient’s preferences and values regarding the benefits and risks of the different treatment options. In this sense, patient decision aids (PtDA) can play...

    Authors: Lilisbeth Perestelo-Pérez, Yolanda Álvarez-Pérez, Amado Rivero-Santana, Vanesa Ramos-García, Andrea Duarte-Díaz, Alezandra Torres-Castaño, Ana Toledo-Chávarri, Mario Herrera-Perez, José Luis País-Brito, José Carlos del Castillo, José Ramón Vázquez, Carola Orrego and Pedro Serrano-Aguilar

    Citation: Trials 2020 21:736

    Content type: Study protocol

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  24. Acute gastroenteritis is a leading cause of emergency department visits and hospitalizations among children in North America. Oral-rehydration therapy is recommended for children with mild-to-moderate dehydrat...

    Authors: Anna Heath, Juan David Rios, Sarah Williamson-Urquhart, Petros Pechlivanoglou, Martin Offringa, Christopher McCabe, Gareth Hopkin, Amy C. Plint, Andrew Dixon, Darcy Beer, Serge Gouin, Gary Joubert, Terry P. Klassen and Stephen B. Freedman

    Citation: Trials 2020 21:735

    Content type: Update

    Published on:

    The Study protocol to this article has been published in Trials 2020 21:435

  25. Primary objective: To estimate the effect of corticosteroids compared with usual care or placebo on mortality up to 28 days after randomization. Secondary objectives: To examine whether the effect of corticost...

    Authors: Jonathan A. C. Sterne, Janet Diaz, Jesús Villar, Srinivas Murthy, Arthur S. Slutsky, Anders Perner, Peter Jüni, Derek C. Angus, Djillali Annane, Luciano Cesar Pontes Azevedo, Bin Du, Pierre-Francois Dequin, Anthony C. Gordon, Cameron Green, Julian P. T. Higgins, Peter Horby…

    Citation: Trials 2020 21:734

    Content type: Letter

    Published on:

  26. Citation: Trials 2020 21:733

    Content type: Correction

    Published on:

    The original article was published in Trials 2020 21:702

  27. Open spina bifida (OSB) is one of the most common congenital central nervous system defects and leads to long-term physical and cognitive disabilities. Open fetal surgery for OSB improves neurological outcomes...

    Authors: Samar Altoukhi, Clare L. Whitehead, Greg Ryan, Jan Deprest, Luc Joyeux, Katie Gallagher, James Drake, Paige Church, Daphne Horn, Yenge Diambomba, Jose C. A. Carvalho and Tim Van Mieghem

    Citation: Trials 2020 21:732

    Content type: Study protocol

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  28. Poor recruitment of patients is the predominant reason for early termination of randomized clinical trials (RCTs). Systematic empirical investigations and validation studies of existing recruitment models, how...

    Authors: Benjamin Kasenda, Junhao Liu, Yu Jiang, Byron Gajewski, Cen Wu, Erik von Elm, Stefan Schandelmaier, Giusi Moffa, Sven Trelle, Andreas Michael Schmitt, Amanda K. Herbrand, Viktoria Gloy, Benjamin Speich, Sally Hopewell, Lars G. Hemkens, Constantin Sluka…

    Citation: Trials 2020 21:731

    Content type: Study protocol

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  29. Cigarette smoking is the leading cause of chronic obstructive pulmonary disease (COPD), and it contributes to the development of many other serious diseases. Smoking cessation in COPD patients is known to impr...

    Authors: Mohamad Isam Saeed, Pradeesh Sivapalan, Josefin Eklöf, Charlotte Suppli Ulrik, Charlotta Pisinger, Therese Lapperre, Philip Tønnesen, Nils Hoyer, Julie Janner, Marie Lavesen Karlsson, Charlotte Sandau Bech, Kristoffer Marså, Nina Godtfredsen, Eva Brøndum, Birgit Munk, Merete Raaschou…

    Citation: Trials 2020 21:730

    Content type: Study protocol

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  30. Lactation has a negative effect on female sexual function. Hormonal changes during lactation cause changes which might lead to dyspareunia, lack of libido, and anorgasmia. There are various pharmacological and...

    Authors: Sanaz Barghamadi, Zainab Alimoardi, Terry Oleson and Nasim Bahrami

    Citation: Trials 2020 21:729

    Content type: Study protocol

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  31. The diagnostic accuracy of CT-derived fractional flow reserve (CT-FFR) in clinical application has been well validated. This advanced technology focus on evaluating anatomical stenosis and functional ischemia ...

    Authors: Junjie Yang, Dongkai Shan, Mei Dong, Zhiqiang Wang, Xiang Ma, Xinyang Hu, Hesong Zeng and Yundai Chen

    Citation: Trials 2020 21:728

    Content type: Study protocol

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  32. Community-acquired pneumonia (CAP) remains a leading cause of death worldwide, and hypoalbuminemia is associated with worse outcomes. However, it remains uncertain whether albumin administration could have any...

    Authors: Alexander Rombauts, Gabriela Abelenda-Alonso, Antonella Francesca Simonetti, Guillermo Verdejo, Yolanda Meije, Lucia Ortega, Mercedes Clemente, Jordi Niubó, Yolanda Ruiz, Carlota Gudiol, Cristian Tebé, Sebastian Videla and Jordi Carratalà

    Citation: Trials 2020 21:727

    Content type: Study protocol

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  33. Hypalbuminemia is associated with numerous postoperative complications, so a perioperative albumin substitution is often considered. The objective of SuperAdd is to investigate whether substitution of human al...

    Authors: Stefan J. Schaller, Kristina Fuest, Bernhard Ulm, Sebastian Schmid, Catherina Bubb, Rüdiger von Eisenhart-Rothe, Helmut Friess, Chlodwig Kirchhoff, Thomas Stadlbauer, Peter Luppa, Manfred Blobner and Bettina Jungwirth

    Citation: Trials 2020 21:726

    Content type: Study protocol

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  34. Hip dysplasia is one of the most common causes of hip arthritis. Its incidence is estimated to be between 3.6 and 12.8% (Canadian Institute for Health Information, Hip and knee replacements in Canada, 2017–201...

    Authors: Geoffrey P. Wilkin, Stéphane Poitras, John Clohisy, Etienne Belzile, Ira Zaltz, George Grammatopoulos, Gerd Melkus, Kawan Rakhra, Tim Ramsay, Kednapa Thavorn and Paul E. Beaulé

    Citation: Trials 2020 21:725

    Content type: Study protocol

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  35. To assess the hypothesis that an adjunctive therapy with methylprednisolone and unfractionated heparin (UFH) or with methylprednisolone and low molecular weight heparin (LMWH) are more effective in reducing an...

    Authors: Stefano Busani, Martina Tosi, Pasquale Mighali, Paola Vandelli, Roberto D’Amico, Marco Marietta, Francesco Forfori, Abele Donati, Gilda Cinnella, Amato De Monte, Daniela Pasero, Giacomo Bellani, Carlo Tascini, Giuseppe Foti, Marco Ranieri and Massimo Girardis

    Citation: Trials 2020 21:724

    Content type: Letter

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  36. Traditional Korean medicine (TKM) has been employed for the treatment of children with cerebral palsy in Korea; however, the addition of TKM to usual rehabilitation (UR) treatment is hindered by insufficient e...

    Authors: Mi-Joo Lee, Young-Ju Yun, Sun-ae Yu, Yong-Beom Shin, Soo-Yeon Kim and Jun-hee Han

    Citation: Trials 2020 21:723

    Content type: Study protocol

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  37. Bubonic plague is the primary manifestation of infection with Yersinia pestis, accounting for 90% of all plague cases and with 75% of global cases reported in Madagascar. All drugs in use for treating plague are ...

    Authors: Rindra Vatosoa Randremanana, Mihaja Raberahona, Mamy Jean de Dieu Randria, Minoarisoa Rajerison, Voahangy Andrianaivoarimanana, Agathe Legrand, Tsinjo Fehizoro Rasoanaivo, Ravaka Randriamparany, Théodora Mayouya-Gamana, Reziky Mangahasimbola, Josie Bourner, Alex Salam, Annelies Gillesen, Tansy Edwards, Matthieu Schoenhals, Laurence Baril…

    Citation: Trials 2020 21:722

    Content type: Study protocol

    Published on:

  38. There remains a paucity of clinical studies assessing how any differences in accuracy of implant positioning between robotic-arm assisted unicompartmental knee arthroplasty (RO UKA) and conventional jig-based ...

    Authors: Babar Kayani, Sujith Konan, Jenni Tahmassebi, Atif Ayuob, Peter D. Moriarty and Fares S. Haddad

    Citation: Trials 2020 21:721

    Content type: Study protocol

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  39. Depression affects approx. 4% of the global population and is often accompanied by insomnia. Medications used to treat insomnia can have side effects such as development of tolerance and addiction. The Protac ...

    Authors: Sanne Toft Kristiansen, Poul Videbech, Merete Bender Bjerrum and Erik Roj Larsen

    Citation: Trials 2020 21:720

    Content type: Study protocol

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  40. Recurrent implantation failure (RIF) brings great challenges to clinicians and causes deep frustration to patients. Previous data has suggested that prednisone may play a promising role in the establishment of...

    Authors: Yao Lu, Junhao Yan, Jiayin Liu, Jichun Tan, Yan Hong, Daimin Wei, Zi-jiang Chen and Yun Sun

    Citation: Trials 2020 21:719

    Content type: Study protocol

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  41. Azithromycin is an orally active synthetic macrolide antibiotic with a wide range of anti-bacterial, anti-inflammatory and antiviral properties. It is a safe, inexpensive, generic licenced drug available world...

    Authors: Timothy S. C. Hinks, Vicki S. Barber, Joanna Black, Susan J. Dutton, Maisha Jabeen, James Melhorn, Najib M Rahman, Duncan Richards, Daniel Lasserson, Ian D. Pavord and Mona Bafadhel

    Citation: Trials 2020 21:718

    Content type: Study protocol

    Published on:

  42. There are no specific generally accepted therapies for the coronavirus disease 2019 (COVID-19). The full spectrum of COVID-19 ranges from asymptomatic disease to mild respiratory tract illness to severe pneumo...

    Authors: Jesús Villar, José M. Añón, Carlos Ferrando, Gerardo Aguilar, Tomás Muñoz, José Ferreres, Alfonso Ambrós, César Aldecoa, Fernando Suárez-Sipmann, Kevin E. Thorpe, Peter Jüni and Arthur S. Slutsky

    Citation: Trials 2020 21:717

    Content type: Study protocol

    Published on:

  43. Prediabetes and diabetes disproportionately impact Latino youth, yet few diabetes prevention programs have prioritized inclusion of this underrepresented population. This report describes the recruitment proce...

    Authors: Kiley B. Vander Wyst, Micah L. Olson, Elva Hooker, Erica G. Soltero, Yolando P. Konopken, Colleen S. Keller, Felipe G. Castro, Allison N. Williams, Arlene D. R. Fernández, Donald L. Patrick, Stephanie L. Ayers, Houchun H. Hu, Armando Peña, Janiel Pimentel, William C. Knowler and Gabriel Q. Shaibi

    Citation: Trials 2020 21:716

    Content type: Methodology

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  44. Mental Health First Aid (MHFA) is a mental health intervention that teaches people how to identify, understand and help someone who may be experiencing a mental health issue. Reviews of the implementation of M...

    Authors: Opeyemi Atanda, Patrick Callaghan, Tim Carter, Graham Durcan, Nick O’Shea, Steve D. Brown, Paula Reavey, Eleni Vangeli, Sarah White and Kerry V. Wood

    Citation: Trials 2020 21:715

    Content type: Study protocol

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  45. Health TAPESTRY (Health Teams Advancing Patient Experience: STRengthening qualitY) aims to help people stay healthier for longer where they live by providing person-focused care through the integration of four...

    Authors: Dee Mangin, Larkin Lamarche, Doug Oliver, Sivan Bomze, Sayem Borhan, Tracy Browne, Tracey Carr, Julie Datta, Lisa Dolovich, Michelle Howard, Sarah Marentette-Brown, Cathy Risdon, Samina Talat, Jean-Eric Tarride, Lehana Thabane, Ruta Valaitis…

    Citation: Trials 2020 21:714

    Content type: Study protocol

    Published on:

  46. In cluster randomized crossover (CRXO) trials, groups of participants (i.e., clusters) are randomly allocated to receive a sequence of interventions over time (i.e., cluster periods). CRXO trials are becoming ...

    Authors: Sheila Sprague, Taryn Scott, Shannon Dodds, David Pogorzelski, Paula McKay, Anthony D. Harris, Amber Wood, Lehana Thabane, Mohit Bhandari, Samir Mehta, Greg Gaski, Christina Boulton, Francesc Marcano-Fernández, Ernesto Guerra-Farfán, Joan Hebden, Lyndsay M. O’Hara…

    Citation: Trials 2020 21:712

    Content type: Methodology

    Published on:

  47. A core outcome set (COS) represents the agreed minimum set of domains and measurement instruments that should be measured and reported in any clinical trial for a given condition. In BMS randomized controlled ...

    Authors: B. Carey, A. M. Farag, C. Nasri-Heir, G. D. Klasser, A. Ariyawardana, M. Chmieliauskaite, A. Sardella, C. R. Carlson, C. S. Miller, L. Mejia, F. E. O’Neill and R. Albuquerque

    Citation: Trials 2020 21:711

    Content type: Study protocol

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  48. Resident-to-resident elder mistreatment (R-REM) is defined as negative and aggressive physical, sexual, or verbal interactions between (long-term care) residents that in a community setting would likely be con...

    Authors: Jeanne A. Teresi, Stephanie Silver, Mildred Ramirez, Jian Kong, Joseph P. Eimicke, Gabriel D. Boratgis, Rhoda Meador, Leslie Schultz, Mark S. Lachs and Karl A. Pillemer

    Citation: Trials 2020 21:710

    Content type: Study protocol

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  49. Recently, we demonstrated that the Montreal Museum of Fine Arts’ (MMFA) participatory art-based activity, known as “Thursdays at the Museum,” improved the well-being, quality of life, and physical health (i.e....

    Authors: Olivier Beauchet, Liam Cooper-Brown, Yoko Hayashi, Kevin Galery, Christine Vilcocq and Thomas Bastien

    Citation: Trials 2020 21:709

    Content type: Study protocol

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  50. Nucleos(t)ide analogues (NAs) are the first-line option against chronic hepatitis B (CHB). NAs produce potent suppression of viral replication with a small chance of HBsAg seroclearance and a high risk of viro...

    Authors: Xiaoke Li, Ludan Zhang, Mei Qiu, Yi Huang, Huanming Xiao, Bingjiu Lu, Yuyong Jiang, Fuli Long, Hui Lin, Jinyu He, Qikai Wu, Mingxiang Zhang, Li Wang, Xiaoning Zhu, Man Gong, Xuehua Sun…

    Citation: Trials 2020 21:708

    Content type: Study protocol

    Published on:

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