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Research
National guidance recommends pregnant women are offered membrane sweeping at term to reduce induction of labour. Local audit suggested this was not being undertaken routinely across two maternity units in the ...
Trials 2017 18:357
Published on: 27 July 2017
Study protocol
Chronic lymphocytic leukaemia (CLL) is the most common adult leukaemia. Achieving minimal residual disease (MRD) negativity in CLL is an independent predictor of survival even with a variety of different treat...
Trials 2017 18:353
Published on: 26 July 2017
Study protocol
Although conventional laparoscopic and hand-assisted laparoscopic surgery for colorectal cancer is widely used today, there remain many technical challenges especially for right colon cancer in obese patients....
Trials 2017 18:355
Published on: 26 July 2017
Research
Describe the prevalence and types of conflicts of interest (COI) in published randomized controlled trials (RCTs) in general medical journals with a binary primary outcome and assess the association between co...
Trials 2017 18:354
Published on: 26 July 2017
Study protocol
Employment protects and fosters health. Occupational health services, particularly in Finland, have a central role in protecting employee health and preventing work ability problems. However, primary care with...
Trials 2017 18:352
Published on: 26 July 2017
Research
Studies evaluating the benefit of adding motivational interviewing (MI) to behavioral weight-loss programs (BWLPs) have yielded mixed findings.
Trials 2017 18:351
Published on: 25 July 2017
Study protocol
Hypotension during anaesthesia for hip fracture surgery is common. Recent data suggest that there is an association between the lowest intra-operative blood pressure and mortality, even when adjusted for co-mo...
Trials 2017 18:350
Published on: 25 July 2017
Study protocol
Despite large-scale efforts to diagnose people living with HIV, 54% remain undiagnosed in sub-Saharan Africa. The gap in knowledge of HIV status and uptake of follow-on services remains wide with much lower ra...
Trials 2017 18:349
Published on: 24 July 2017
Research
The United States Food and Drug Administration (FDA) reviews class III orthopedic devices submitted for premarket approval with pivotal clinical trials. The purpose of this study was to determine the types of ...
Trials 2017 18:348
Published on: 24 July 2017
Study protocol
The coracoid approach is recognized as the simplest approach to perform brachial plexus anaesthesia, but needle visualization needs to be improved. With a different needle entry point, the retroclavicular appr...
Trials 2017 18:346
Published on: 21 July 2017
Study protocol
Depression is a common illness with great human costs and a significant burden on the public economy. Previous studies have indicated that collaborative care (CC) has a positive effect on symptoms when provide...
Trials 2017 18:344
Published on: 21 July 2017
Study protocol
Clinical placements are a critical component of the training for health professionals such as occupational therapists. However, with growing student enrolments in professional education courses and workload pr...
Trials 2017 18:345
Published on: 21 July 2017
Study protocol
Atopic eczema (AE) is a common skin problem that impairs quality of life and is associated with the development of other atopic diseases including asthma, food allergy and allergic rhinitis. AE treatment is a ...
Trials 2017 18:343
Published on: 21 July 2017
Study protocol
The effectiveness of nonpharmacological interventions in blood pressure reduction has been evidenced by several studies. Nevertheless, as adherence to a low-sodium diet is poor, interventions regarding habit c...
Trials 2017 18:347
Published on: 21 July 2017
Research
Retention of participants in cohort studies is important for validity. One way to promote retention is by sending a persuasive cover letter with surveys. The study aimed to compare the effectiveness of a cover...
Trials 2017 18:341
Published on: 20 July 2017
Study protocol
Loss of arm function is a common and distressing consequence of stroke. We describe the protocol for a pragmatic, multicentre randomised controlled trial to determine whether robot-assisted training improves u...
Trials 2017 18:340
Published on: 20 July 2017
Meeting abstracts
Trials 2017 18(Suppl 2):244
Published on: 20 July 2017
This article is part of a Supplement: Volume 18 Supplement 2
Research
The Cessation in Pregnancy Incentives Trial (CPIT), which offered financial incentives for smoking cessation during pregnancy showed a clinically and statistically significant improvement in cessation. However...
Trials 2017 18:337
Published on: 20 July 2017
Study protocol
The selection of appropriate outcomes or domains is crucial when designing clinical trials, to appreciate the effects of different interventions, pool results, and make valid comparisons between trials. If the...
Trials 2017 18:336
Published on: 20 July 2017
Study protocol
Despite the reduction in glycemic derangement in patients with type 1 diabetes mellitus (T1D) through dietary and therapeutic adjustments implemented before, during and after continuous exercise, evidence for ...
Trials 2017 18:338
Published on: 20 July 2017
Study protocol
People with decompensated cirrhosis require complex medical care and are often prescribed an intricate and frequently changing medication and lifestyle regimen. However, many patients mismanage their medicatio...
Trials 2017 18:339
Published on: 20 July 2017
Study protocol
Depression is a highly prevalent and costly disorder. Effective treatments are available but are not always delivered to the right person at the right time, with both under- and over-treatment a problem. Up to...
Trials 2017 18:342
Published on: 20 July 2017
Commentary
Reproducibility, data sharing, personal data privacy concerns and patient enrolment in clinical trials are huge medical challenges for contemporary clinical research. A new technology, Blockchain, may be a key...
Trials 2017 18:335
Published on: 19 July 2017
Study protocol
Despite a variety of efficient and cost-effective antihypertensive medication, hypertension remains a serious health and economic burden. High consumption of cardiovascular drugs in the Slovak Republic does re...
Trials 2017 18:334
Published on: 18 July 2017
Review
Selective clinical trial publication and outcome reporting has the potential to bias the medical literature. The 2007 Food and Drug Administration (FDA) Amendment Act (FDAAA) mandated clinical trial registrati...
Trials 2017 18:333
Published on: 18 July 2017
