CRRT screening | CRRT randomization | Beta-blocker screening | Beta-blocker randomization | Days post-randomization | ||||
---|---|---|---|---|---|---|---|---|
Day 3 | Day 7 | Day 30 | Day 365 | |||||
Window for time for evaluation | ± 5 days | ± 35 days | ||||||
Visit number | 1 | 1 | 2 | 3 | 4 | 5 | ||
Informed consent | × | × | ||||||
Demographic data | × | × | ||||||
Physical measures | × | × | × | × | ||||
Medical history | × | × | ||||||
Concomitant medications | × | × | × | × | × | × | × | × |
Physical examinationsa | × | × | ||||||
Vital signsb | × | × | × | × | ||||
Complete blood countc | × | × | × | × | ||||
Arterial blood gasd | × | × | × | × | ||||
Biochemistry itemse | × | × | × | × | ||||
Coagulation indexesf | × | × | × | × | ||||
UCGg | × | × | × | × | ||||
Intake and output volume in 24 h | × | |||||||
Medication, type, and doseh | × | × | × | × | × | × | ||
Mechanical ventilation and mode | × | × | × | × | × | |||
Left ventricular unloading method | × | × | × | |||||
RRT | × | × | × | × | × | |||
APACHE II score | × | × | ||||||
SOFA score | × | × | ||||||
EQ-5D score | × | |||||||
SAEs | × | × | ×: | × |