INCLUSION CRITERIA |
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Male or female age 18 years or older. |
Patients with stable angina pectoris and/or documented ischemia due to multivessel disease and preserved ventricular function. |
Angiographically confirmed multivessel CAD lesions with ≥70% in at least 2 major epicardial vessels and at least 2 separate coronary artery territories: LAD, LCX, and RCA. |
Patients who are eligible for coronary surgery both with and without cardiopulmonary bypass circuit. |
Nonsignificant left main stenoses can be included. |
Willing to comply with all follow-up study visits. |
Signed and received a copy of the informed consent. |
EXCLUSION CRITERIA |
Age under 18 years |
Severe congestive hearth failure NYHA Class III or IV or pulmonary edema. |
Prior valve replacement or CABG coronary surgery. |
Prior PCI with stent implantation within 6 months. |
Prior stroke within 6 months or patients with stroke at more than 6 months with significant residual neurological involvement, as reflected in a Rankin score > 1. |
Need for concomitant major surgery, eg, valve replacement, resection ventricular aneurysm, congenital heart disease vascular surgery of the carotid artery, or thoracic-abdominal aorta. |
Concomitant medical disorders making clinical follow-up at least 5 years unlikely or impossible, eg, neoplasic, hepatic, or other severe disease. |
Q-wave myocardial infarction in the previous 6 weeks. |
Hemorrhagic diathesis or hypercoagulability. |
Thoracic deformations technically precluding surgery without extracorporeal circulation. |
Unable to give informed consent. |