Recruitment and retention of young women into nutrition research studies: practical considerations
Trials volume 15, Article number: 23 (2014)
Successful recruitment and retention of participants into research studies is critical for optimising internal and external validity. Research into diet and lifestyle of young women is important due to the physiological transitions experienced at this life stage. This paper aims to evaluate data related to recruitment and retention across three research studies with young women, and present practical advice related to recruiting and retaining young women in order to optimise study quality within nutrition research.
Recruitment and retention strategies used in three nutrition studies that targeted young women (18 to 35 years) were critiqued. A randomised controlled trial (RCT), a crossover validation study and a cross-sectional survey were conducted at the University of Newcastle, Australia between 2010 and 2013Successful recruitment was defined as maximum recruitment relative to time. Retention was assessed as maximum participants remaining enrolled at study completion.
Recruitment approaches included notice boards, web and social network sites (Facebook and Twitter), with social media most successful in recruitment. The online survey had the highest recruitment in the shortest time-frame (751 participants in one month). Email, phone and text message were used in study one (RCT) and study two (crossover validation) and assisted in low attrition rates, with 93% and 75.7% completing the RCT and crossover validation study respectively. Of those who did not complete the RCT, reported reasons were: being too busy; and having an unrelated illness.
Recruiting young women into nutrition research is challenging. Use of social media enhances recruitment, while Email, phone and text message contact improves retention within interventions. Further research comparing strategies to optimise recruitment and retention in young women, including flexible testing times, reminders and incentives is warranted.
Attracting young women to participate in nutrition, health and medical research is essential in developing translatable diet, health and lifestyle education programs relevant to their life stage . However, difficulties exist in recruiting young women and keeping them involved in research studies . Very little research into factors affecting their recruitment and engagement in nutrition research has been conducted . From the limited research conducted to date, some common challenges have been highlighted, such as making initial contact, arranging mutually suitable times for data collection, maintaining contact for study duration and reducing attrition [2, 4, 5]. These challenges appear to be less prevalent in the recruitment and retention of young men .
Two common recruitment goals are to obtain a sample sufficient to represent the target population and to recruit adequate numbers, with power to test the primary hypothesis . Difficulty recruiting participants can disrupt the study timeline and consequently strain resources and ability of researchers to complete the study as planned within budget and time limits . Strategies traditionally used to recruit young women have included random digit dialing, media and community advertising campaigns or university-based recruitment .
Challenges of making initial contact with young women and then maintaining it appear to be associated with age-normative transitional events , including commencement of university studies, moving residence, commencing new employment, travelling overseas, and time constraints related to work, study, co-habitation, family and peers. Strategies commonly used to facilitate retention include the use of phone calls, sending out reminder text messages, Email reminders or mail [2, 5].
New methods to recruit young women are being explored and include the use of social media such as Facebook and Twitter [9, 10]. There is growing evidence on the use of social media for study recruitment . Many social interactions with young women occur via the Internet, therefore social networking sites are being utilised more frequently to recruit participants . The Australian Longitudinal Study of Women’s Health (ALSWH) is now recruiting a new young cohort of females aged 18 to 23 years. Recruitment for this new young cohort is being conducted using the ALSWH website, which includes a link to their Facebook page and Twitter account, and offers incentives to participants . The use of social media in recruitment is somewhat limited in its ability to reach individuals who have little or no access to the Internet, however, having Internet access is very common. The Australian Communications and Media Authority reported that as of June 2013, 10.8 million Australians accessed the Internet once per day, a 7% increase from June 2008 . Also in 2012, a US report confirmed that Internet usage was not restricted to higher socio-economic status with 75% of lower socio-economic individuals using the Internet and 66% of adult Internet users accessing social media sites .
In this paper, we examine recruitment and retention across three recent studies in young women. Our aim is to address the practical considerations surrounding recruitment and retention at this life stage and to make recommendations for optimising these aspects within future research.
Comparative analysis of the processes used to recruit and retain young women in three research studies conducted at The University of Newcastle, New South Wales, Australia was conducted. Methodological details for each study, participant characteristics and retention rate are outlined in Table 1. Effectiveness of recruitment and retention was compared based on the numbers of women who contacted researchers and expressed initial interest in participation; numbers screened for eligibility; numbers eligible/ineligible for study inclusion and reason for ineligibility; numbers commencing the study; numbers completing the study; and reasons for withdrawing.
Study one was a double-blind, placebo-controlled, randomized trial. The aim was to examine the efficacy of iron supplementation in iron deficient women and its effect on cognitive function. Pre and post assessments involved completing a 50 minute computer-based cognition test, and having a blood sample taken on campus. Iron deficient participants and a proportion of iron sufficient participants continued to the intervention phase where they were given placebo, 60 mg or 80 mg elemental iron for 16 weeks. The target sample was 120 women. Participants received personal feedback regarding their blood test results.
Study two used a randomised crossover design to compare the accuracy and acceptability of a web-based food diary completed via computer, to a food diary accessed via a Smartphone, to a paper-based food diary. Young women (18 to 30 years of age) completed all three food diary modes, over three separate seven-day periods with the order of completion assigned randomly (days 2 to 8, days 16 to 22 and days 30 to 36). On day 1, participants’ resting energy expenditure was measured via indirect calorimetry, as well as their height and body composition. From day 2 to day 8, their physical activity levels were monitored via accelerometry. On days 1, 9, 15, 23, 29 and 37, their weight was measured, and on days 9, 23 and 37, they completed a survey regarding the acceptability of the food diary completed. Participants attended assessment sessions on six occasions over 37 days, during which measures were taken for demographics, weight, height, and body composition. The length of sessions varied from ten minutes to one hour, depending on which assessments were being measured. The target sample was 40 women.
Study three was a brief (approximately 15 minutes) online cross-sectional survey to identify expectations of an eHealth weight management intervention (for example, mode of delivery, content, features). The aims were also to identify barriers to weight loss overall, as well as specific barriers to participating and engaging in an eHealth weight loss intervention. The target sample was at least 100 women.
Comparing the effectiveness of recruitment
In study one a total of 155 participants expressed interest in participating from June 2010 to March 2013. Of these, 128 participants met eligibility criteria. The recruitment methods used during the first 12 months were flyers on campus notice boards at the University of Newcastle and the Newcastle Technical and Further Education (TAFE) College, Emails to University staff, promotion in lectures and word-of-mouth. Seventy three participants (57% of eligible participants) were recruited within the initial 12 months. From 2012 to 2013 recruitment was extended to the wider community and included flyers in gyms and day care centres, word-of-mouth, and Facebook messages. Advertising the study in the Research Awareness Exercise Program for two University courses (psychology and nursing) was also included. Participation in a research awareness program enabled students to receive course credit for their participation, with 15 participants (12% of total) recruited via this method. Another approach undertaken from 2012 to 2013 was to extend community-based recruitment and utilise the Hunter Medical Research Institute (HMRI) volunteer register. Questionnaires were sent to 250 females who had placed themselves on the register, resulting in recruitment of 10 participants (8% of total). Repeating community-based methods and refreshing University campus flyers attracted the final 30 participants from 2012 to March 2013.
In study two, 91 individuals expressed interest, of whom 22 participated (24%). For this study, flyers were displayed on University campus noticeboards and Emailed to staff and students. The University’s media unit also advertised it on the University website news, with a link to the story placed on the University’s Facebook site, and details released via Twitter.
In study three, the recruitment methods used generated the required study sample (> 100) one month, the shortest time frame of the three included studies. The study was advertised via the University’s media unit on the University website news, and promoted on the University’s social media sites (Facebook and Twitter). Invitations to participate were also distributed to staff and students across various University Email lists. Participants were encouraged to share the survey link at the end of the study with their friends via social networks or Email. Of the 798 individuals who expressed interest, 751 (94%) were assessed as eligible, and 570 (71.4%) completed the full survey (see Table 2).
Reasons for ineligibility
In study one, of the 134 participants who completed eligibility screening, six participants were not eligible. Of these, one was unable to attend the assessment session at the University, two were male and three had donated blood within three months prior to screening.
Study two screened 83 women, of whom 61 were ineligible. Of these, 22 did not meet body mass index (BMI) criteria, 18 were unable to make the assessment sessions at the University, six did not meet the definition for weight stability in the previous three months, five did not have a Smartphone, five were unwilling to remain weight stable during the study period, two were smokers, two had chronic health issues and one had no access to the Internet.
Study three screened 780 women, of these 29 were deemed ineligible. Four were male, 13 did not meet age criteria and 12 did not live in Australia. As shown in Table 2, 18 of the 798 did not complete the eligibility screening questions.
Retention strategy effectiveness
Retention strategies used by study one and study two are summarised in Table 1, and include text message and Email reminders. Of the 128 eligible for study one, 95 (74%) provided complete data sets at baseline testing, 32 were subsequently enrolled in the RCT of whom 26 (81%) completed the 16 week intervention and follow-up testing. Of the six participants who commenced but did not complete the intervention, reasons given for withdrawing included unrelated illness (n = 4) or being too busy (n = 2).
Methods used to assist with retention and adherence in study one included optional text message reminders, a paper-based calendar, a small capsule container for carrying supplements in a handbag, and four-weekly symptom check phone calls. These methods are detailed in Table 1. Only 10/32 participants opted to have text message reminders sent to them. All ten of these participants reported that they liked receiving the reminders. All except one participant in study one remained contactable by phone or Email for the entirety of the study. Of the 124 capsules provided to participants, the average number of capsules remaining and returned to researchers was 12 ± 12 (9.6%). Data on the number of capsules missed indicated that receiving a text message reminder made no difference to the number of capsules missed.
All 22 women in study two had completed the study within a six-month recruitment period (January to June 2012) but only 18 completed more than 85% of recording days for each diary and provided enough data to be included in the study analysis.
This paper examined data related to recruitment and retention of young women across three different research study designs in order to address the practical issues related to their participation and representation within research. The results showed that the use of social media, text messages and face-to-face contact were beneficial in the recruitment of young women into nutrition research studies. These results are similar to those of a 2009 Cochrane Review by Mapstone et al.  that identified 15 trials evaluating the effectiveness of strategies to improve recruitment in research. They reported that trials using monetary incentives, and treatment information on the consent form demonstrated benefit . Furimsky et al. (2008) examined the challenges of recruiting and retaining youth with mental illness within RCTs and found incentives and flexibility in scheduling useful . Neither of these studies examined the influence of gender on recruitment.
Adamson et al. (2007) scrutinized recruitment strategies used in the Australian Longitudinal Study on Women’s Health (ALSWH). Authors reported on the importance of piloting recruitment strategies and keeping records of recruitment successful processes . They also recommended ensuring contact could be made easily by participants and in 1996 when this study was recruiting this was by providing a free call number to participants and obtaining as many inward phone lines as possible. At this time, when there was limited access to the Internet, phone contact was one of the easiest methods of accessing participants as it provided an instant response.
Each of the three studies examined in this paper placed recruitment information on social networks online and found such strategies particularly useful when recruiting this demographic. A recent study by Fenner et al. also found modern information and communication technologies useful in assisting in engaging young women in health research . Findings demonstrating the utility of recruiting young participants using social media sites, such as Facebook and Twitter are not surprising when you consider that three-quarters of adult Internet users under the age of 25 users have profiles on social media sites . The large number of people connected to the Internet means a large potential pool of participants . Study one had social media added to recruitment methods after an initial 12 months of slow recruitment. Study two used social media from the beginning of recruitment and recruited 22 participants within four months, which was slightly slower than study one, which recruited 31 participants within the same timeframe. Study three recruited 751 participants in one month. It is important to note that both study one and two (crossover validation) had reasonably stringent eligibility criteria and had higher levels of participant burden than study three, therefore making recruitment more difficult. Reasons for ineligibility were recorded for each study, which gave insight about the barriers to successful enrolment into a study, even after individuals have expressed interest in research studies. A barrier is not being able to attend the face-to-face assessment sessions.
Study one also included a mail-out of study information to volunteers who had placed themselves on a research register, in its recruitment methods. Less than 10% of participants were recruited using this method. This recruitment rate was considerably lower than the 40% response rate reported by . Potential reasons for the low number of participants recruited via this method in study one may be the time burden associated with having to attend the University for blood and cognition tests.
Traditional methods such as flyers, PowerPoint slides in lectures, staff and student Email lists were used by the studies. These methods were effective in recruiting the majority of the participants in study one, however, resulted in slow recruitment, and required regular refreshing of flyers on the noticeboards.
Direct comparison of recruitment between the three studies included was not an aim due to differences in the degree of burden associated with participation, and in the difference influence of incentives across the studies. The blood test required for study one was the most significant participant burden of the three studies. Study one also included taking capsules every day for a 16-week period. Study two involved burden associated with completing lengthy food records and having six face-to-face assessments. High participant burden is more likely to be acceptable if the personal benefit of study results is also high. For example, the numbers of iron deficient females volunteering for the RCT early on in recruitment was significantly greater than the previously reported prevalence of iron deficiency in this age group, suggesting that these participants potentially had personal health benefits as a factor motivating participation.
Previous research has shown that when recruiting for an RCT, the use of incentives such as feedback, course credit, money or ‘lottery’ is useful . Various incentives were offered in all studies. Study one offered individual feedback on blood test results and study two offered feedback on participants’ diets.
Study one was advertised to students in psychology and nursing courses that offer course credit for research participation. Both psychology and nursing are large courses at the University of Newcastle (950 and 1,500 students, respectively) with high percentages of females. The ‘value’ of the credit is limited to five (nursing) or ten (psychology) marks out of 100 and it seems this may not be adequate incentive for large numbers of students to participate. In addition, students may have other research studies competing for their interest.
Studies two and three offered vouchers as incentives for participants. The chance to win ten shopping vouchers valued at 150 dollars is likely to have assisted in the recruitment of 400 participants (70%) within the first day of online recruitment into study three. The addition of a monetary or voucher based incentive may have improved recruitment for study one.
The lower burden of the cross-sectional design, not involving blood testing, capsules or extensive food diaries  and the short one-off online survey with an incentive of prize draws is very likely to have made study three more appealing to participants. It is possible to recruit a lot of young women quite quickly if incentive prize draws are offered and combined with the convenience on online participation that is one-off. The National Statement on Ethical Conduct in Human Research in Australia approve the reimbursement of participants for costs associated with participation, however, state that it is unacceptable to provide payment to participants that is disproportionate to the time involved or encourages them to take risks .
Our findings suggest that text reminders, phone calls and face-to-face contact may improve retention of young women in nutrition research, however further research is required to compare different incentives and contact methods to enable more definitive conclusions. The recruitment of young males into research may also benefit from using the strategies identified and further research in young males is required.
Recommendations for researchers
A number of key recommendations emerge from our examination of recruitment and retention methods across three studies:
Social networking sites should be utilised to distribute or advertise the study.
Consider participants’ motivation for participating, such as health benefits or incentives.
Use appropriate reimbursement or incentives such as monetary reward relative to the time demand involved, vouchers and course credit that are targeted to the population group.
Be flexible regarding testing days and times and provide individual feedback of results where appropriate.
Speak with participants in person or on phone calls as soon as possible to build researcher-participant rapport.
Use Email, phone calls, text messages and face-to-face contact as much as possible to maintain communication with participants.
This paper aimed to address the practical considerations surrounding recruitment and retention of young women in research studies. Recruiting young women for intervention trials is challenging. However, strategies such as using technologies (for example, social networking, Email, text messages) already used by young women can facilitate both recruitment and retention. The appropriate use of incentives and Email or phone reminders are important and should be planned from the start in order to optimize retention and study quality, statistical power and research outcomes.
Study one was supported by Meat and Livestock Australia, studies two and three by the Priority Research Centre in Physical Activity and Nutrition. Alecia J Leonard receives a University of Newcastle Scholarship and a top-up scholarship from Meat and Livestock Australia. Clare E Collins is supported by a National Health and Medical Research Council Australian Career Development Fellowship.
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The authors declare that they have no competing interests.
AL made substantial contribution to conception and design; conducted one of the studies analysed and significantly contributed to the preparation and revision of the manuscript. MH conducted two of the studies analysed and was involved in the drafting and critical revision of the manuscript for important intellectual content. AP, KC and CC were involved in the drafting and critical revision of the manuscript for important intellectual content. All authors have contributed and approved the final version of the manuscript.
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Leonard, A., Hutchesson, M., Patterson, A. et al. Recruitment and retention of young women into nutrition research studies: practical considerations. Trials 15, 23 (2014). https://doi.org/10.1186/1745-6215-15-23
- Young women
- Nutrition study