Skip to main content

Articles

Page 5 of 176

  1. Premenstrual syndrome (PMS) is one of the most widespread menstrual disorders in women of reproductive age. This recurrent syndrome is a combination of physically, mentally, or behaviorally disturbing changes ...

    Authors: Zainab Alimoradi, Somayeh Rajabalipour, Khaled Rahmani and Amir H. Pakpour
    Citation: Trials 2022 23:346
  2. Though the Rwandan Ministry of Health (MOH) prioritizes the scale-up of postpartum family planning (PPFP) programs, uptake and sustainability of PPFP services in Rwanda are low. Furthermore, highly effective l...

    Authors: Kristin M. Wall, Rosine Ingabire, Amelia Mazzei, Claudine Umuhoza, Rachel Parker, Amanda Tichacek, Azhar Nizam, Jessica M. Sales, Lisa B. Haddad, Phaedra Corso, Susan Allen, Julien Nyombayire and Etienne Karita
    Citation: Trials 2022 23:337
  3. Authors: Sarah Halford, Susan Wan, Ilaria Dragoni, Julie Silvester, Bobojon Nazarov, Daniel Anthony, Suzie Anthony, Emma Ladds, John Norrie and Kevin Dhaliwal
    Citation: Trials 2022 23:336

    The original article was published in Trials 2021 22:550

  4. Current hyponatraemia guidelines are divided on the use of tolvaptan in hospitalised patients with moderate to severe hyponatraemia, due to an uncertain risk-benefit ratio. We will conduct a randomised trial t...

    Authors: Annabelle M. Warren, Mathis Grossmann, Rudolf Hoermann, Jeffrey D. Zajac and Nicholas Russell
    Citation: Trials 2022 23:335
  5. Peripheral arterial disease is a progressive atherosclerotic disease with symptoms ranging from an intermittent claudication to acute critical limb ischemia and amputations. Drug-coated balloons and stents wer...

    Authors: Stefano Barco, Tim Sebastian, Davide Voci, Rolf Peter Engelberger, Alexandru Grigorean, Erik Holy, Claudia Leeger, Mario Münger, Daniel Périard, Eliane Probst, Rebecca Spescha, Ulrike Held and Nils Kucher
    Citation: Trials 2022 23:334
  6. There is a large unused potential for risk reduction in the preoperative period via effective lifestyle intervention targeting co-existing risky lifestyles: Smoking, malNutrition, obesity, risky Alcohol intake...

    Authors: Hanne Tønnesen, Line Noes Lydom, Ulla Nordström Joensen, Ingrid Egerod, Helle Pappot and Susanne Vahr Lauridsen
    Citation: Trials 2022 23:333
  7. We conducted in-depth interviews to characterize reasons for COVID-19 vaccine hesitancy in emergency department (ED) patients and developed messaging platforms that may address their concerns. In this trial, w...

    Authors: Robert M. Rodriguez, Kelli O’Laughlin, Stephanie A. Eucker, Anna Marie Chang, Kristin L. Rising, Graham Nichol, Alena Pauley, Hemal Kanzaria, Alexzandra T. Gentsch, Cindy Li, Herbie Duber, Jonathan Butler, Vidya Eswaran and Dave Glidden
    Citation: Trials 2022 23:332
  8. Chronic kidney disease (CKD) is a very common long-term condition and powerful risk factor for cardiovascular disease (CVD).

    Authors: Hugh Gallagher, Jennifer Dumbleton, Tom Maishman, Amy Whitehead, Michael V. Moore, Ahmet Fuat, David Fitzmaurice, Robert A. Henderson, Joanne Lord, Kathryn E. Griffith, Paul Stevens, Maarten W. Taal, Diane Stevenson, Simon D. Fraser, Mark Lown, Christopher J. Hawkey…
    Citation: Trials 2022 23:331
  9. Clinical research should provide reliable evidence to clinicians, health policy makers, and researchers. The reliability of evidence will be assured once study planning, conducting, and reporting of results ar...

    Authors: Kinga Amália Sándor-Bajusz, Andrea Kraut, Odgerel Baasan, Gergely Márovics, Károly Berényi and Szimonetta Lohner
    Citation: Trials 2022 23:330
  10. Evidence concerning the effect of Tai Chi Yunshou motor imagery training (TCY-MIT) on upper extremity motor function (UE-MF) recovery in poststroke patients is lacking, and few studies have examined the neural...

    Authors: Lin Hong Jiang, Li Juan Zhao, Yang Liu, Hong Zhang, Si Cong Zhang, Wei Qin Cong and Rui Qi
    Citation: Trials 2022 23:329
  11. Adolescents growing up in communities characterised by adversity face multiple risk factors for poor mental health and wellbeing. There is currently a scarcity of research on effective approaches for preventin...

    Authors: Felicity L. Brown, Tania Bosqui, Joseph Elias, Sally Farah, Anas Mayya, Diana Abo Nakkoul, Bryony Walsh, Sarah Chreif, Ahmad Einein, Bassel Meksassi, Roula Abi Saad, Hady Naal, Maliki E. Ghossainy, Michael Donnelly, Theresa S. Betancourt, Alan Carr…
    Citation: Trials 2022 23:327
  12. Physical exercise is a first-line treatment for peripheral arterial disease (PAD) and intermittent claudication (IC) reducing pain and increasing the distances walked. Home-based exercise therapy (HBET) has th...

    Authors: Ivone Silva, Susana Pedras, Rafaela Oliveira, Carlos Veiga and Hugo Paredes
    Citation: Trials 2022 23:326
  13. Household air pollution is a leading health risk for global morbidity and mortality and a major health risk in South Asia. However, there are no prospective investigations of the impact of household air pollut...

    Authors: Camille Raynes-Greenow, Ashraful Alam, Sk Masum Billah, Sajia Islam, Kingsley Agho, S. M. Rokonuzzaman, Jonathan Thornburg, Shams El Arifeen, Atique Iqbal Chowdhury and Michael J. Dibley
    Citation: Trials 2022 23:325
  14. Postictal phenomena as delirium, headache, nausea, myalgia, and anterograde and retrograde amnesia are common manifestations after seizures induced by electroconvulsive therapy (ECT). Comparable postictal phen...

    Authors: Joey P. A. J. Verdijk, Julia C. M. Pottkämper, Esmée Verwijk, Guido A. van Wingen, Michel J. A. M. van Putten, Jeannette Hofmeijer and Jeroen A. van Waarde
    Citation: Trials 2022 23:324
  15. Knee osteoarthritis (OA) is a leading cause of global disability. According to current guidelines, exercise is the most recommended and important non-surgical treatment for knee OA. However, the best type of e...

    Authors: Ruiyang Li, Pingping Sun, Yu Zhan, Xuetao Xie, Weibing Yan and Congfeng Luo
    Citation: Trials 2022 23:323
  16. Retinopathy of prematurity (ROP) eye examination screening presupposes adequate mydriasis for an informative fundoscopy of preterm infants at risk, on a weekly basis. Systemic absorption of the instilled mydri...

    Authors: Aikaterini K. Seliniotaki, Anna-Bettina Haidich, Maria Lithoxopoulou, Helen Gika, Eleftheria Boutou, Christina Virgiliou, Martha Nikolaidou, Aristides Dokoumetzidis, Nikolaos Raikos, Elisavet Diamanti, Nikolaos Ziakas and Asimina Mataftsi
    Citation: Trials 2022 23:322
  17. Polymyalgia rheumatica (PMR) is an inflammatory rheumatic disease affecting people older than 50, resulting in pain and stiffness of the neck, shoulder, and pelvic girdle. To date, glucocorticoids (GC) remain ...

    Authors: Diane E. Marsman, Thomas E. Bolhuis, Nathan den Broeder, Alfons A. den Broeder and Aatke van der Maas
    Citation: Trials 2022 23:318
  18. The prevalence rates of gout worldwide have increased annually. Acute gouty arthritis (AGA) accounts for a large proportion of gout patients and causes severe physical and mental pain in patients. Controlling ...

    Authors: Yikun He, Chaoran Dai, Jiaying Shen, Qianwen Chen, Jiandong Gao, Xin Pan and Jing Gan
    Citation: Trials 2022 23:317
  19. Atrial fibrillation (AF) is one of the most common cardiac arrhythmia diseases. Thromboembolic prophylaxis plays an essential role in AF therapy, but at present, general practitioners (GPs) are presumed to lac...

    Authors: Xueying Ru, Lan Zhu, Yunhui Ma, Tianhao Wang and Zhigang Pan
    Citation: Trials 2022 23:316
  20. Clinical recommendations suggest exercises as the main treatment modality for patients with knee osteoarthritis (OA). This study aimed to compare the effects of two different exercise interventions, i.e., open...

    Authors: Wei Hui Ng, Nazatul Izzati Jamaludin, Farhah Nadhirah Aiman Sahabuddin, Shaifuzain Ab Rahman, Amran Ahmed Shokri and Shazlin Shaharudin
    Citation: Trials 2022 23:315
  21. LGBT patients may have unique psychosocial cancer care needs, and healthcare providers should have knowledge and understanding of these unique needs to effectively address disparities through the delivery of p...

    Authors: Julia Seay, Eryk N. Hernandez, Jaileene Pérez-Morales, Gwendolyn P. Quinn and Matthew B. Schabath
    Citation: Trials 2022 23:314
  22. Perinatal depression, especially minor depression, is common during pregnancy and is likely to continue into the postpartum period. It may impair the mother’s health, the infant’s neurodevelopment, and the mot...

    Authors: Henrika Pulliainen, Sari-Ahlqvist-Björkroth and Eeva Ekholm
    Citation: Trials 2022 23:313
  23. Patients with acute brain injury often require invasive mechanical ventilation, increasing the risk of developing complications such as respiratory secretions retention. Rapid chest compression is a manual che...

    Authors: Ricardo Miguel Rodrigues-Gomes, Joan-Daniel Martí, Rosa Martínez Rolán and Miguel Gelabert-González
    Citation: Trials 2022 23:312
  24. The phenomenon of restlessness, agitation, or cognitive disturbances experienced by dying patients is well-known in palliative care; more than half of these patients will experience delirium symptoms at end-of...

    Authors: Xiao-Juan Lyu, Adrian David Kan, Poh-Heng Chong, Keegan Lin, Yung-Hua Koh and Zhi-Zheng Yeo
    Citation: Trials 2022 23:311
  25. COVID-19 has impacted the health and social fabric of individuals and families living across the USA, and it has disproportionately affected people living in urban communities with co-morbidities, those workin...

    Authors: Liliane Windsor, Ellen Benoit, Rogério M. Pinto and Jesus Sarol
    Citation: Trials 2022 23:310
  26. Otitis media with effusion (OME) is common and occurs at disproportionately higher rates among Indigenous children. Left untreated, OME can negatively affect language, development, learning, and health and wel...

    Authors: Robyn Walsh, Jennifer Reath, Hasantha Gunasekera, Amanda Leach, Kelvin Kong, Deborah Askew, Federico Girosi, Wendy Hu, Timothy Usherwood, Sanja Lujic, Geoffrey Spurling, Peter Morris, Chelsea Watego, Samantha Harkus, Cheryl Woodall, Claudette Tyson…
    Citation: Trials 2022 23:309
  27. Diabetes mellitus is one of the four priority non-communicable diseases worldwide. It can lead to serious long-term complications and produces significant costs. Due to the chronicle character of the disease, ...

    Authors: Elisabeth Höld, Johanna Grüblbauer, Martin Wiesholzer, Daniela Wewerka-Kreimel, Stefan Stieger, Werner Kuschei, Philip Kisser, Elisabeth Gützer, Ursula Hemetek, Astrid Ebner-Zarl and Jürgen Pripfl
    Citation: Trials 2022 23:308
  28. Chronic obstructive pulmonary disease (COPD) is associated with significant morbidity, mortality and healthcare costs. Beta blockers are well-established drugs widely used to treat cardiovascular conditions. O...

    Authors: Seonaidh Cotton, Graham Devereux, Hassan Abbas, Andrew Briggs, Karen Campbell, Rekha Chaudhuri, Gourab Choudhury, Dana Dawson, Anthony De Soyza, Shona Fielding, Simon Gompertz, John Haughney, Chim C. Lang, Amanda J. Lee, Graeme MacLennan, William MacNee…
    Citation: Trials 2022 23:307
  29. Active participation in intellectual leisure activities such as calligraphy helps prevent cognitive decline and dementia, but the underlying mechanisms are not fully understood. With disrupted functional conne...

    Authors: Rachel W. K. Yan, Charlotte P. C. Kwok, Jessie O. T. Kwok, Kaspar K. W. Lee, Hanna Lu, Winnie C. W. Chu, Timothy C. Y. Kwok, Linda C. W. Lam and Allen T. C. Lee
    Citation: Trials 2022 23:306
  30. Type 2 diabetes mellitus (T2DM) is a common metabolic disease with significant health, social, and economic consequences. Traditional Chinese medicine (TCM) could effectively regulate blood sugar and influence...

    Authors: Li Jiang, Qiang Fu, Shidong Wang, Yu Chen, Jiayue Li, Yonghua Xiao, Ruixi Sun, Esther Aijia Shen, Junheng Wang, Yaofu Zhang, Zhuang Li, Jiangteng Liu, Xiaozhe Fu, Yuanyuan Liu, Yu Zhao, Guanxun Su…
    Citation: Trials 2022 23:305
  31. Malaysia has an estimated hepatitis C virus (HCV) prevalence of 1.9% among its adult population and a history of providing HCV treatment in the public sector. In 2019, Malaysia launched a 5-year national strat...

    Authors: Sonjelle Shilton, Xiaohui Sem, Huan-Keat Chan, Han Yang Chung, Anu Karunanithy, Jessica Markby, Po-Lin Chan, Niklas Luhmann, Cheryl Johnson, Pamela Nabeta, Nazrila Hairizan Bt Nasir, Stefano Ongarello, Elena Ivanova Reipold and Muhammad Radzi Abu Hassan
    Citation: Trials 2022 23:304
  32. COVID-19 has quickly become a global pandemic with a substantial number of deaths and is a considerable burden for healthcare systems worldwide. Although most cases are paucisymptomatic and limited to the vira...

    Authors: Pierre Malchair, Aurema Otero, Jordi Giol, Xavier Solanich, Thiago Carnaval, Alonso Fernández-Nistal, Ana Sánchez-Gabriel, Carmen Montoto, Ramon Lleonart and Sebastián Videla
    Citation: Trials 2022 23:303
  33. Proton-pump inhibitors (PPI) are liberally prescribed in patients with liver cirrhosis. Observational studies link PPI therapy in cirrhotic patients with an increased risk for infectious complications, hepatic...

    Authors: Malte H. Wehmeyer, Thomas Horvatits, Anika Buchholz, Linda Krause, Sarah Walter, Antonia Zapf, Ansgar W. Lohse and Johannes Kluwe
    Citation: Trials 2022 23:302
  34. Functional task performance requires proper control of both movement and force generation in three-dimensional space, especially for the hand. Control of force in three dimensions, however, is not explicitly t...

    Authors: Na Jin Seo, Derek G. Kamper, Viswanathan Ramakrishnan, Jillian B. Harvey, Christian Finetto, Christian Schranz, Gabrielle Scronce, Kristen Coupland, Keith Howard, Jenna Blaschke, Adam Baker, Caitlyn Meinzer, Craig A. Velozo and Robert J. Adams
    Citation: Trials 2022 23:301
  35. The trial investigates the efficacy of internet-based cognitive behavioral therapy (iCBT) in improving health-related QoL in patients with endometriosis, which is a chronic gynecological condition affecting up...

    Authors: Kathrin Schubert, Johanna Lohse, Matthias Kalder, Volker Ziller and Cornelia Weise
    Citation: Trials 2022 23:300
  36. Among the challenges of living with lower limb loss is the increased risk of long-term health problems that can be either attributed directly to the amputation surgery and/or prosthetic rehabilitation or indir...

    Authors: William Anderst, Goeran Fiedler, Kentaro Onishi, Gina McKernan, Tom Gale and Paige Paulus
    Citation: Trials 2022 23:299
  37. It has been recognized that oral health education for parents is critical for preventing early childhood caries (ECC). Few parents practiced caries prevention procedures for their children in daily life, thoug...

    Authors: Ketian Wang, Gillian Hiu Man Lee, Pei Liu, Xiaoli Gao, Samuel Yeung Shan Wong and May Chun Mei Wong
    Citation: Trials 2022 23:298
  38. With increasing obese populations worldwide, developing interventions to modulate food-related brain processes and functions is particularly important. Evidence suggests that transcranial direct current stimul...

    Authors: Peyman Ghobadi-Azbari, Nastaran Malmir, Meghedi Vartanian, Rasoul Mahdavifar-Khayati, Somaye Robatmili, Venus Hadian, Sara Derafsheh, Michael A. Nitsche, Masoud Nosratabadi, Ali Farhoudian and Hamed Ekhtiari
    Citation: Trials 2022 23:297
  39. Orthopaedic surgeries include some of the highest volume surgical interventions globally; however, studies have shown that a significant proportion of patients report no clinically meaningful improvement in pa...

    Authors: Madeleine Hinwood, Laura Wall, Danielle Lang, Zsolt J. Balogh, Angela Smith, Michelle Dowsey, Phillip Clarke, Peter Choong, Samantha Bunzli and Francesco Paolucci
    Citation: Trials 2022 23:296
  40. Ultrasound-guided intertruncal approach (IA) has been proposed to be an alternative and promising approach to the supraclavicular block (SCB), in which double injection (DI) of local anesthetics (LA) is sequen...

    Authors: Quehua Luo, Huiying Liu, Longjiao Deng, Lidan Nong, Haifeng Li, Yujing Cai, Junyi Zheng, Haihua Shu, Weifeng Yao and Jianxing Zhang
    Citation: Trials 2022 23:295
  41. Sepsis and continuous renal replacement therapy (CRRT) are both responsible for the alterations of the pharmacokinetics of antibiotics. For patients with sepsis receiving CRRT, the serum concentrations of mero...

    Authors: Sui-Qing Ni, Wen-Bing Teng, Yong-Hong Fu, Wei Su, Zhi Yang, Jie Cai, Jin-Nuo Xu, Xiao-Ying Deng, Xiang-Fang Liu, Sheng-Nan Fu, Jun Zeng and Chen Zhang
    Citation: Trials 2022 23:294
  42. Meta-analysis from previous studies have shown that treatment with mesenchymal stromal cell (MCSs) may increase the left ventricular ejection fraction (LVEF) after acute myocardial infarction (AMI) by 3.84%, a...

    Authors: Armin Attar, Fatemeh Nouri, Arash Yazdanshenas, Kamran Hessami, Massoud Vosough, Alireza Abdi-Ardekani, Peyman Izadpanah, Mani Ramzi, Javad Kojouri, Gholamreza Pouladfar and Ahmad Monabati
    Citation: Trials 2022 23:293
  43. Intermittent exotropia (IXT) is the most common type of exotropia in China. Surgery is usually required to align the eye deviation to maintain or obtain better binocular visual function. However, there is a hi...

    Authors: Meiping Xu, Fuhao Zheng, Yiyi Peng, Chunxiao Wang, Jiangtao Lou, Huanyun Yu, Yuwen Wang and Xinping Yu
    Citation: Trials 2022 23:289
  44. Approximately one fifth of Australian males aged 16+ experience mood, anxiety or substance use disorders in a given year, and suicide by males accounts for three quarters of all suicides annually. However, mal...

    Authors: Angela Nicholas, Simone Scotti Requena, Maria Ftanou, Simon Rice, Justine Fletcher, Andrew Mackinnon, Zac Seidler, Long Khanh-Dao Le, Cathrine Mihalopoulos and Jane Pirkis
    Citation: Trials 2022 23:288
  45. Positive Choices is a whole-school social-marketing intervention to promote sexual health among secondary school students. Intervention comprises the following: school health promotion council involving staff ...

    Authors: Ruth Ponsford, Rebecca Meiksin, Elizabeth Allen, G. J. Melendez-Torres, Steve Morris, Catherine Mercer, Rona Campbell, Honor Young, Maria Lohan, Karin Coyle and Chris Bonell
    Citation: Trials 2022 23:287

    The Study protocol to this article has been published in Trials 2021 22:818

  46. Heart failure (HF) with reduced ejection fraction (HFrEF) is a syndrome that leads to fatigue and reduced functional capacity due to disease-related pathophysiological mechanisms. Aerobic exercise (AERO) plays...

    Authors: Leandro T. Franzoni, Eduardo L. Garcia, Stephanie B. Motta, Mabel M. Ahner, Otávio A. Bertoletti, Marco A. L. Saffi, Anderson D. da Silveira, Alexandre A. Pereira, Adamastor H. Pereira, Luiz C. Danzmann and Ricardo Stein
    Citation: Trials 2022 23:283

Annual Journal Metrics