Table 4 Generic recommendations to promote coordination and optimal use of resources in platform trials
Consider adaptive platform trials as public health research instruments |
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Avoid development of overlapping platform trials |
Avoid competition between platform trials (in terms of sites, patient recruitment, intervention arms) |
Promote coordination between platform trial managers |
Build a trusted dialogue and cooperation mechanisms between investigators of platform trials addressing the same diseases |
Establish an independent board providing scientific assessment and prioritising the candidate intervention arms |
Use this independent board to distribute the new intervention arms to the best adapted platform trial |