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Fig. 2 | Trials

Fig. 2

From: The clinical value of mNGS of bronchoalveolar lavage fluid versus traditional microbiological tests for pathogen identification and prognosis of severe pneumonia (NT-BALF):study protocol for a prospective multi-center randomized clinical trial

Fig. 2

The schedule of enrolment, intervention and assessments. TMT, traditional microbiological tests; EOT, end of therapy; E, discharge from the ICU. “*” symbol indicates baseline variables: age, gender, BMI (body mass index), history of smoking, comorbidity, etc. “^” symbol indicates primary outcome: 28-day all-cause mortality. “#” symbol indicates secondary outcome: (1) ICU and hospital length of stay (LOS), (2) ventilator-free days and ICU-free days, (3) consistency between mNGS and traditional microbiological tests, (4) detective rate of mNGS and traditional microbiological tests, (5) turn-out time, (6) types and duration of anti-infective regimens, (7) source of drug-resistant bacteria or fungi, and (8) ICU cost

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