Adjustment of positive end-expiratory pressure to body mass index during mechanical ventilation in general anesthesia: BodyVent, a randomized controlled trial

Table 1 Outcome definition

Domain	Respiratory mechanics	Rescue therapy	Hemodynamics	Postoperative status
Specific measures	• Driving pressure • Mechanical power of ventilation (elastic-dynamic, tidal, and total) • Compliance of respiratory system	• Number of alveolar recruitment maneuvers	• Intraoperative fluid requirements • Average intraoperative vasopressor requirements • Number of intraoperative hypotension events • time-weighted average of hypotension	• SpO₂ after arrival in recovery room • Number of patients with additional oxygen insufflation^a • Change in lung aeration score
Specific metric	Difference between control and intervention group	Difference between control and intervention group	Difference between control and intervention group	Difference between control and intervention group
Method of aggregation	Mean + SD (parametric data) or Median/IQR (non-parametric data)	Mean + SD (parametric data) or Median/IQR (non-parametric data)	Mean + SD (parametric data) or Median/IQR (non-parametric data)	Mean + SD (parametric data) or Median/IQR (non-parametric data) and four-square table^a
Time point	Intraoperative	Intraoperative	Intraoperative	Postoperative

Outcomes are defined following the framework of Saldanha et al. [20]
^aFour-square table is only used as method of aggregation for “number of patients with additional oxygen insufflation”

ISSN: 1745-6215