Table 3 Effect of iron supplementation on primary and secondary outcomes (intention-to-treat population)
Outcome variable | Haem iron | Ferrous sulphate | Group difference, unadjusted (95% CI) | p-value | Group difference, adjusted (95% CI) | p-value |
|---|---|---|---|---|---|---|
Serum iron, μmol/L | – | – | – | – | – | – |
Serum ferritin, μg/L | – | – | – | – | – | – |
Serum soluble transferrin receptor, mg/L | – | – | – | – | – | – |
Serum transferrin, g/L | – | – | – | – | – | – |
UIBC, μmol/L | – | – | – | – | – | – |
TSAT | – | – | – | – | – | – |
Serum sTfR/log10(ferritin) index | – | – | – | – | – | – |
Haemoglobin, g/dL | – | – | – | – | – | – |
Anaemia (haemoglobin < 11.0 g/dL) | – | – | – | – | – | – |
MCV, fL | – | – | – | – | – | – |
MCH, pg | – | – | – | – | – | – |
MCHC, g/dL | – | – | – | – | – | – |
Reticulocyte count, × 109/L | – | – | – | – | – | – |
Reticulocyte count, % | – | – | – | – | – | – |
Immature reticulocyte fraction, % | – | – | – | – | – | – |
Reticulocyte haemoglobin, pg | – | – | – | – | – | – |
Serum hepcidin, μg/L | – | – | – | – | – | – |
Serum erythropoietin, IU/L | – | – | – | – | – | – |
Serum erythroferrone, μg/L | – | – | – | – | – | – |
Serum C-reactive protein, mg/L | – | – | – | – | – | – |
Serum α1-acid glycoprotein, g/L | – | – | – | – | – | – |
Height-for-age z-score, SD | – | – | – | – | – | – |
Weight-for-age z-score, SD | – | – | – | – | – | – |
Height-for-weight z-score, SD | – | – | – | – | – | – |