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Fig. 3 | Trials

Fig. 3

From: Trials that turn from retrospectively registered to prospectively registered: a cohort study of “retroactively prospective” clinical trial registration using history data

Fig. 3

Movements of start dates from launch to 5 years, for 113 published retroactively prospective trials and 177 published controls. Many control trials keep their original start date, and among those that do not, only some of the prospectively registered trials move their start dates around (which would be expected). Among the retroactively prospective trials, however, some get moved forward by quite a bit, with the 5-year start date lying just after the first registration mark. The dotted line represents the 21-day grace period granted by the FDA

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