Table 1 Advantages and disadvantages of industrial funding in RCTs
Definition | Advantages | Disadvantages |
|---|---|---|
Non-industry-funded trials are clinical studies or trials funded by sources other than the pharmaceutical, medical device, or biotechnology industries. These sources may include academic institutions, government agencies, non-profit organizations, or individual donors | Answer questions that the industry may not be willing to or is uninterested to study Answer questions of interest to clinicians and patients Less influence of industry on study design and conduct Less concern for commercial interests Potentially lower risk of publication bias Team building across countries | Reliability of endpoints other than all-cause mortality Limited financial resources Limited access to specialized equipment or technologies Smaller sample size due to limited funding Fewer resources for marketing and disseminating results Often does not follow the standard required by FDA/EMA Difficulty in recruiting participants due to limited resources Legal and ethical issues regarding data transfer across borders |