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Fig. 2 | Trials

Fig. 2

From: Pragmatic randomized controlled trials: strengthening the concept through a robust international collaborative network: PRIME-9—Pragmatic Research and Innovation through Multinational Experimentation

Fig. 2

Comparison of Bayesian and frequentist statistics. A Bayesian analysis workflow—this panel illustrates the essential components of Bayesian analysis, including the incorporation of prior probabilities, the calculation of likelihood based on observed data, and the computation of posterior probabilities using Bayes’ theorem. The iterative nature of Bayesian updating is also depicted, highlighting the adaptability of the approach as new evidence becomes available. B Frequentist analysis workflow—in contrast, this panel demonstrates the frequentist analysis workflow, which involves estimating parameters based solely on the likelihood of observed data. The focus is on hypothesis testing and the calculation of p-values, without the incorporation of prior knowledge

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