Table 5 Optimal number of sites and total study costs by METRC Coordinating Center costs model
Cost model 1 | Cost model 2 | Cost model 3 | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
MCC costs a | Low: $133,056 | Intermediate: $362,736 | High: $1,132,560 | |||||||
Studyb | Actual number of sites used | Optimal number of sites | Years | Total costs | Optimal number of sites | Years | Total costs | Optimal number of sites | Years | Total costs |
BIOBURDEN | 34 | 10 | 6.33 | $1,262,405 | 14 | 5.53 | $1,596,196 | 20 | 5.04 | $2,569,073 |
CBPT | 9 | 4 | 2.08 | $1,349,289 | 6 | 1.69 | $1,453,665 | 6 | 1.69 | $1,821,734 |
FIXIT | 37 | 6 | 8.15 | $1,499,032 | 13 | 6.48 | $1,899,148 | 15 | 6.33 | $3,083,458 |
NERVE | 17 | 6 | 4.17 | $724,495 | 10 | 3.89 | $934,055 | 15 | 3.14 | $1,582,993 |
OUTLET | 27 | 8 | 4.91 | $1,900,871 | 14 | 3.80 | $2,143,628 | 20 | 3.36 | $2,821,824 |
OXYGEN | 29 | 7 | 5.96 | $1,237,749 | 11 | 5.29 | $1,563,808 | 20 | 4.60 | $2,491,668 |
PAIN | 25 | 6 | 5.23 | $1,950,631 | 10 | 4.40 | $2,217,465 | 14 | 4.06 | $3,008,738 |
POvIV | 28 | 5 | 7.63 | $962,856 | 10 | 6.60 | $1,368,154 | 15 | 6.16 | $2,543,342 |
pTOG | 17 | 9 | 5.59 | $352,652 | 12 | 5.08 | $666,424 | 12 | 5.08 | $1,623,751 |
STREAM | 52 | 6 | 5.22 | $524,679 | 13 | 4.00 | $787,874 | 20 | 3.54 | $1,508,087 |
TAOS | 28 | 10 | 7.67 | $1,981,525 | 17 | 6.13 | $2,351,391 | 23 | 5.67 | $3,446,207 |
VANCO | 35 | 7 | 3.94 | $1,309,569 | 14 | 2.94 | $1,497,082 | 23 | 2.54 | $2,040,911 |