Table 1 Oropharyngeal cancer risk categories
Risk group | Definition | 3-year OS (95% CI) | 3-year LRC rate | UK incidence: proportion of OPC cases | Projected no. per year |
|---|---|---|---|---|---|
Low-risk | HPV+ve non-smokers (or smoke < 10 pack years) with small nodal disease (N0–N2a) and T1–3 tumours | 93% (88.3–97.7) | 90.4 | 33% | 596 |
Intermediate-risk | HPV+ve with advanced nodal disease (N2b/c, N3) and > 10 pack year smoking or T4 tumour HPV-ve non-smokers with T1–3 tumours | 70.8% (60.7–80.8) | 80.9 | 47% | 829 |
High-risk | HPV-ve smoking associated with T4 tumour | 46% (34.7–57.7) | 57.3 | 20% | 343 |