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Fig. 2 | Trials

Fig. 2

From: Study protocol for a randomised cross-over trial of Neurally adjusted ventilatory Assist for Neonates with Congenital diaphragmatic hernias: the NAN-C study

Fig. 2

Ventilation protocol for the NAN-C trial. At King’s College Hospital NHS Foundation Trust (KCH), infants are routinely ventilated using assist control ventilation on the SLE 6000 ventilator. If infants meet the eligibility criteria, they will be transferred from ACV on the SLE 6000 to ACV on the servo-n ventilator (in the above diagram, ventilation machine changes depicted by arrows). Infants will be stabilised on the servo-n ventilator for 1 h in the ventilatory support tolerance trial. If suitable, infants will then be randomised to receive either ACV or neutrally adjusted ventilator assist (NAVA) for 4 h. Following a 20-min stabilisation period, they will then receive the second mode of ventilation. At St. George’s University Hospital (SGH), infants are routinely ventilated on ACV on the servo-n ventilator. Following the VSTT, they will be randomised to either NAVA or ACV on the servo-n ventilator

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Trials

ISSN: 1745-6215