1st visit on FET initial day | 2nd visit after enrollment | 3rd visit after 5 days | 4th visit after 10 days | 5th visit on ET | 1st follow-up at 14 days after ET | 2nd follow-up at 5 weeks after ET | 3rd follow-up at mid-pregnancy | End of live birth | |
---|---|---|---|---|---|---|---|---|---|
Enrollment | |||||||||
Eligibility screen | X | ||||||||
Written informed consent | X | ||||||||
Allocation | X | ||||||||
Interventions | |||||||||
Optimal endometrial preparation | X | X | X | X | X | ||||
Lactobacillus capsule | X | X | X | ||||||
Assessments | |||||||||
Baseline questionnaire | X | ||||||||
Vaginal and cervical canal swabs | X | X | |||||||
Peripheral blood samples | X | X | |||||||
Medication diary (intervention group) | X | X | X | ||||||
HCG and P | X | X | |||||||
Clinical pregnancy | X | ||||||||
Maternal and Fetal information | X | X | X | ||||||
Safety assessment | X | X | X | X | X | X | X | X |