Study Period | Timepoint | Assessments |
---|---|---|
Enrolment | Day 0–1 | Eligibility |
Informed consent | ||
Allocation | Baseline information | |
PaO2/FiO2 ratio after receiving HFNO therapy for 2Â h | ||
Post-allocation | During interventions (Day 1–termination) | Vital signs |
PaO2/FiO2 ratio | ||
Borg scale | ||
Position changing time (experimental groups only) | ||
ROX index | ||
Special treatments | ||
Respiratory support | ||
Adverse events | ||
At discharge/Day 28 | Hospitalisation cost | |
Number of hours using HFNO | ||
Number of hours using advanced respiratory support mode | ||
Number of hours using conventional oxygen therapy | ||
Length of hospital and ICU stay | ||
Close-out | At Day 28 | Death |
Endotracheal intubation |