Table 2 Clinical Trials Questionnaire responses

I thought the trial offered the best treatment available

159 (91%)

6 (29%)

54.6

< 0.001^a

35 (20%)

1 (6%)

I believed the benefits of treatment would out-weigh any side effects

142 (82%)^b

1 (5%)

56.6

< 0.001

5 (3%)

0 (0%)

I was satisfied that either treatment in the trial would be suitable for me

141 (81%)

6 (29%)

27.0

< 0.001

7 (4%)

0 (0%)

I was worried that my illness would get worse unless I joined the study

29 (17%)

1 (5%)^b

1.8

0.3^a

0 (0%)

1 (6%)

The idea of randomisation worried me

84 (48%)

16 (76%)

6.0

0.02

1 (1%)

3 (17%)

I wanted the doctor to choose my treatment rather than be randomised by computer

69 (39%)

15 (71%)

7.8

0.005

0 (0%)

1 (5%)

The doctor told me what I needed to know about the trial

171 (98%)

19 (91%)

3.3

0.1^a

0 (0%)

0 (0%)

I trusted the doctor treating me

173 (99%)

19 (95%)^b

1.8

0.3^a

7 (4%)

0 (0%)

I was given too much information to read about the trial

29 (17%)

0 (0%)

4.1

0.05^a

0 (0%)

0 (0%)

I was given enough information to read about the trial

170 (97%)

17 (81%)

11.2

0.009^a

6 (3%)

3 (17%)

I knew I could leave the trial at any time and still be treated

175 (100%)

18 (86%)

25.4

< 0.001^a

23 (13%)

2 (11%)

I did not feel able to say no

13 (7%)

1 (5%)

0.2

1.000^a

0 (0%)

0 (0%)

I wanted to help the doctors research

166 (95%)

11 (55%)^b

34.0

< 0.001^a

34 (19%)

1 (6%)

I feel that others with my illness will benefit from results of the trial

174 (99%)

12 (57%)

69.0

< 0.001^a

55 (31%)

0 (0%)

The doctor wanted me to join the trial

62 (35%)

5 (25%)^b

0.9

0.4

1 (1%)

1 (6%)

Others (e.g. family or friends) wanted me to join the trial

83 (47%)

1 (5%)

13.9

< 0.001

1 (1%)

5 (28%)