An integrated personalized assistive devices approach to reduce the risk of foot ulcer recurrence in diabetes (DIASSIST): study protocol for a multicenter randomized controlled trial

Table 1 Average predicted costs per participant

				Enhanced therapy		Usual care
Modality	Event/activity	Time (hours)	Unit costs	Expected frequency	Expected costs	Expected frequency	Expected costs
	Ulcer development [6]	-	€10,000	0.15	€1500	0.37	€3700
	Podiatrist	1	€100	0.50	€50	0.00	€0
Custom-made footwear	Optimization equipment: pressure measurements [36]	-	€50	1.00	€50	0.00	€0
	Shoe technician	1	€100	2.00	€200	0.00	€0
Custom-made indoor footwear	Production and optimization [13]	-	€400	0.95	€380	0.00	€0
Personalized temperature monitoring	Thermometry [38]	-	€75	0.75	€56.25	0.00	€0
Personalized education	Structured education	1	€100	0.50	€50	0.00	€0
	Motivational Interviewing	1	€100	2.00	€200	0.00	€0
	Equipment [49, 57]	-	€100	1.00	€100	0.00	€0
Total					€2,586.25		€3,700

Average of predicted additional costs per participant of enhanced therapy versus usual care, based on the expected frequencies as described in the power calculation. For all costs except ulcer development, usual care is used as index. Unit cost estimations are based on previous studies and standard hourly wages of a college educated professional in the Netherlands

ISSN: 1745-6215