Table 3 The schedule of enrolment, randomisation, assessments and follow-up

Review eligibility criteria

X

X

Written informed consent

X

Demographic data and medical history

X

Questionnaires: KDQoL, EQ-5D-5L, PSQI, SONG-HD, TTR

X

X

X

X

MoCA

X

X

X

Baseline health economics questionnaire

X

Randomisation

X

Intradialytic urine collection and paired blood samples*

X

X

Serum beta-2 microglobulin*

X

X

X

X

X

X

X

Resource use and expenditure questionnaire

X

X

X

Routine clinical data^◊ including adherence, dialysis adequacy, blood pressure and monthly blood results

X

X

X

X

X

X

X

Capture of routine clinical data and resource usage (UKRR, SRR, HES, ONS, ISD)

X