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Fig. 2 | Trials

Fig. 2

From: Leukocyte- and platelet-rich fibrin in endoscopic endonasal skull base reconstruction: study protocol for a multicenter prospective, parallel-group, single-blinded randomized controlled non-inferiority trial

Fig. 2

Flowchart of “L-PRF in endoscopic endonasal skull base reconstruction.” After obtaining informed consent, patients are screened and asked to complete general and disease-specific quality of life (QoL) questionnaires (EQ-5D, VAS, SNOT-22, and SBI). Preoperative MR images are assessed for tumor size and location. During surgery, study subjects are randomized into experimental arm (treated with L-PRF) and control arm (commercially available fibrin sealants). Clinical follow-up visits with an endoscopic examination of the operation wound are organized at 2, 4, and 12 weeks postop. At these visits, QoL questionnaires are completed as well. MR imaging is performed at 12 weeks postop

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Trials

ISSN: 1745-6215