Table 2 Participant timeline

Enrolment

 Eligibility check

x

 Valid informed consent

x

 Randomisation^C

x

Baseline medical and demographic data

 Medical history

x

 Baseline clinical assessments^D

x

 Lung function tests (FEV₁, FVC, DLCO)^E

x

Clinical data

 Trial intervention

x

 Complications of regional anaesthesia^F

x

x

x

x

x

 Resource use (analgesics use etc.)

x

x

x

x

x

x

x

x

 Mortality check

x

x

x

x

x

x

x

x

 Post-operative surgical complications

x

x

x

x

x

 Post-operative pulmonary complications

x

x

x

x

x

 SAE check

x

x

x

x

x

x

x

x

Patient reported data

 Pain questionnaires (VAS, BPI)

x

x

x

x

x

x

x^G

x

 Pain questionnaire (SF-MPQ-2)

x

x

x

x

x

 Quality of life questionnaires (EQ-5D-5L and HADS)

x

x

x

x

x

 Patient Satisfaction (patient questionnaire)

x

x

x

x

 Out of pocket costs incurred by participants

x

x

x

 Societal cost (productivity loss etc.)

x

x

x