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Table 3 Exclusion criteria

From: Rivaroxaban in patients with abdominal aortic aneurysm and high-sensitivity C-reactive protein elevation (BANBOO): study protocol for a randomized, controlled trial

Exclusion criteria

1. ACS (unstable angina and acute myocardial infarction)

2. Dual antiplatelet therapy for stable CHD less than 6 months after PCI or ACS less than 1 year after PCI

3. Acute congestive heart failure or left ventricular ejection fraction ≤ 40%

4. Suffered from infectious diseases within 2 months before screening and infection has not been controlled more than 1 month

5. Active hepatitis, the elevation of alanine aminotransferase (ALT) value > 5 × the upper limit of normal

6. Severe renal failure (CrCl < 30 ml/min)

7. Life expectancy is less than 1 year

8. Any situation may interfere with the research process, such as dementia, paralysis, alcoholism, etc

9. Pregnancy or women during the lactation period

10. Suffered from hereditary connective tissue disease, such as Marfan’s syndrome, etc

11. Known allergies or intolerance to aspirin or rivaroxaban

12. AAA tends to rupture or has ruptured, and abdominal pain aggravates

13. Major surgery within 1 month

14. Active stage of severe peptic ulcer or previous bleeding events (including retinal or vitreous hemorrhage, urinary tract hemorrhage, etc.) within 6 months

15. Have participated in other ongoing clinical studies

16. Refuse to provide a written informed consent

17. Other unsuitable conditions adjudicated by investigators

  1. ACS acute coronary syndrome, CHD coronary heart disease, PCI percutaneous coronary intervention, CrCl creatinine clearance rate, CrCl = body weight(kg) × (140-age)/[0.818 × CREA(μmol/L)][serum creatinine (CREA) is tested by enzymatic method. Female: above data results × 0.85]