Exclusion criteria |
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1. ACS (unstable angina and acute myocardial infarction) |
2. Dual antiplatelet therapy for stable CHD less than 6Â months after PCI or ACS less than 1Â year after PCI |
3. Acute congestive heart failure or left ventricular ejection fraction ≤ 40% |
4. Suffered from infectious diseases within 2Â months before screening and infection has not been controlled more than 1Â month |
5. Active hepatitis, the elevation of alanine aminotransferase (ALT) value > 5 × the upper limit of normal |
6. Severe renal failure (CrCl < 30 ml/min) |
7. Life expectancy is less than 1Â year |
8. Any situation may interfere with the research process, such as dementia, paralysis, alcoholism, etc |
9. Pregnancy or women during the lactation period |
10. Suffered from hereditary connective tissue disease, such as Marfan’s syndrome, etc |
11. Known allergies or intolerance to aspirin or rivaroxaban |
12. AAA tends to rupture or has ruptured, and abdominal pain aggravates |
13. Major surgery within 1Â month |
14. Active stage of severe peptic ulcer or previous bleeding events (including retinal or vitreous hemorrhage, urinary tract hemorrhage, etc.) within 6Â months |
15. Have participated in other ongoing clinical studies |
16. Refuse to provide a written informed consent |
17. Other unsuitable conditions adjudicated by investigators |