Effects of adjuvant application of corticosteroid and ozone after ultrasound-guided puncture and lavage for the treatment of rotator cuff calcific tendinitis: study protocol for a non-inferiority randomized controlled trial

Table 1 Schedule of enrolment, interventions, and outcome assessment

	Study period
Action/timepoint	Enrolment	Intervention phase	Follow- up
Action/timepoint	Enrolment	Intervention phase	1 week	1 month	3 months	6 months	12 months
Eligibility screen	×
Informed consent	×
History and physical examination	×
X-rays	×		×		×		×
Randomization	×
Interventions
UGPL + steroid injection		×
UGPL + ozone injection		×
Assessment
NRS	×		×	×	×	×	×
WORC	×		×	×	×	×	×
UCLASS	×		×	×	×	×	×
DASH	×		×	×	×	×	×
RC-QOL	×		×	×	×	×	×
Calcification absorption			×		×		×
Multiple treatments^a				×	×	×	×
Adverse events		×	×	×	×	×	×

UGPL ultrasound-guided puncture and lavage, NRS numeric rating scale, WORC Western Ontario Rotator Cuff index, UCLASS the University of California at Los Angeles shoulder scale, DASH Disabilities of the Arm, Shoulder and Hand, RC-QOL Rotator Cuff Quality-of-life Messure
^aIf required

ISSN: 1745-6215