Table 3 Anticipated interactions between subject characteristics and the intervention effect
Characteristic | Anticipated outcomes impacted and direction a,b,c,d,e,f,g,h | Rationale |
|---|---|---|
Residence-to-NICU distance | Families with greater residence-to-NICU distance will have greater intervention effect compared to families with shorter distance a,e | The intervention will be particularly helpful for parents with more barriers to travel |
California HPI | Families with lower HPI (from neighborhoods with fewer resources) will have greater intervention effect compared to those with higher HPI a,e | The intervention will be particularly helpful for families from neighborhoods with fewer resources |
Parent race and ethnicity | Parents of minority races and ethnicities will have greater intervention effect compared to non-Latinx White parents a,g | Using our pilot trial [24] data, among the control arm, the weighted incidence rate for the FCR parent attendance proportion for racial and ethnic minority subjects (relative to non-Latinx White subjects) was 0.32 (95% CI 0.20–0.50). Among the intervention arm, the weighted incidence rate became 0.68 (95% CI 0.56–0.83). The rigorous comparison of these two ratios revealed that the IRR for minority subjects*intervention interaction was 2.15 (95% CI 1.30–3.56) i |
Parent transportation security | Families with transportation insecurity will have greater intervention effect compared to families with access to adequate transportation a,e | The intervention will be particularly helpful for parents with more barriers to travel |
Other children dependents | Parents with other children dependents will have greater intervention effect compared to parents without other children dependents a,e | The intervention will be particularly helpful for parents with other children dependents; virtual FCR will mitigate barriers to attend FCR due to competing childcare responsibilities |
Parent computer/smart device access | Parents lacking computer/smart device access will have lower intervention effect compared to those with access a | Parents lacking computer/smart device access will have fewer resources to attend FCR—either in-person or virtually |
Parent internet access | Parents with no/limited internet access will have lower intervention effect compared to those with high speed access a | Parents with no/limited internet access will have fewer resources to attend FCR—either in-person or virtually |
Parent digital literacy score | Parents with lower digital literacy will have lower intervention effect compared to those with high digital literacy a | Parents with lower digital literacy will have greater challenges in using the intervention |