Table 1 Data generating processes by data source and indicator
Data source | Description of data | Used to estimate |
|---|---|---|
Tuberculosis treatment register | For all participants enrolled in the trial, baseline data are collected from the facility tuberculosis treatment register, including gender, age, HIV and ART status and treatment history From this register, the following outcomes will be abstracted, including cured, treatment completed, treatment failure, death, loss to follow-up, not evaluated and moved to the MDR register. The following patient resource-use data collected (1) number of tuberculosis diagnostics and (2) number of months on tuberculosis treatment | Resource use Treatment outcomes |
Baseline socio-demographic survey | All participants enrolled on the trial are interviewed at enrolment to collect baseline demographic information as well as information to estimate household socio-economic position | Household socio-economic position |
12-month follow-up survey | Participants enrolled on the trial with successful (completed/cure) end-of-treatment outcomes will be interviewed 12Â months after enrolment to confirm their treatment outcomes and to ask additional questions about their resource use during the preceding year, including (3) number of hospitalisations and nights in hospital, (4) number of adherence support home visits and (5) treatment restarted | Resource use |
Health facility visits log | Completed by healthcare workers in the trial facility and (6) number of visits made to a trial health facility | Resource use |
Substudy 1 patient survey | This survey will be implemented in a subsample of 15 (of 78) health facilities. In each health facility, approximately 10 trial participants will be recruited to complete a survey on patient costs incurred. Purposive sampling will be used to sample participants who are in the intensive versus continuation phase of treatment and to achieve a balanced sample of men and women. Patient resource use data that will be collected include (7) number of visits to a private health facility and (8) number of phone calls related to adherence | Patient unit costs Resource use |
Facility surveys A and B | HCWs from a subsample of 15 (of 78) health facilities, will be asked to collect using the facility costing data related to the cost of healthcare worker time collection tool. The time spent by healthcare workers on activities related to treatment adherence will be collected using two facility surveys: Survey 1: healthcare workers will be asked to, over a period of 6Â weeks, record the time they spend on treatment support-related tasks during interactions with 10 consecutive participants Survey 2: asked to retrospectively record time spent on administrative tasks weekly for 6Â weeks | Provider unit costs |
Cost data collection tool | Used to collect data on facility overhead costs (such as building space, maintenance, utilities and management staff). These costs will be allocated to the tuberculosis programme and to the individual patient level using the proportion of human resource time as the allocation factor | Overhead costs |
Visits and calls ASCENT-platform | Project staff logs their interactions with health facility staff (visits and calls) in supporting the implementation of DATs and responding to queries related to the ASCENT adherence platform | Intervention costs |
KNCV project records | Training logs and project expenditure reports of the cost of procuring and distributing DATs will be collected | Intervention costs |