Arthroscopic synovectomy versus intra-articular injection of corticosteroids for the management of refractory psoriatic or rheumatoid arthritis of the wrist: study protocol for a randomized controlled trial (ARCTIC trial)

Table 1 Trial schedule according to the recommendation for interventional trial (SPIRIT) guidelines

	Enrolment	Allocation	Post-allocation
Timepoint**	14 days (± 4 days) prior to intervention	Intervention	Week 2	Week 4	Week 6	Month 3	Month 6	Month 12
Enrolment
Eligibility screen	X
Informed consent	X
Allocation	X
Interventions
Arthroscopic synovectomy		X
Intra-articular corticosteroid injection		X
Assessments
Questionnaires (PRWE, EQ-5D-5L, iMCQ, iPCQ)	X					X	X	X
Physical exam (including ROM, GS and DAS28)	X					X	X	X
Wrist ultrasound	X					X
Plain wrist radiographs	X							X
Blood parameters (ESR, CRP)	X					X	X	X
NRS pain scores	X		X	X	X	X	X	X
Complications and secondary treatment			X	X	X	X	X	X
Cost-effectiveness analysis								X

ISSN: 1745-6215