Mapping the methodological diversity of published drug discontinuation studies—a scoping review of study topics, objectives, and designs

Table 5 Motivation for conducting drug discontinuation trial: investigators’ perspective (n = 574)

	n	Col %
High risk for drug toxicity	280	48.8
Investigating efficacy by discontinuation	124	21.6
Doubts regarding benefit in particular group or case	79	13.8
Changed management of condition (e.g., medication will be exchanged through another therapy)	42	7.3
Insufficient evidence for medication	33	5.7
High costs	14	2.4
High interaction risk	2	0.3

ISSN: 1745-6215