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Table 4 Numbers of patients diagnosed with schizophrenia or schizoaffective disorder prescribed LAI antipsychotics from 2007 to 2016*

From: Can multisite clinical trial results change clinical practice? Use of long-acting injectable risperidone nationally in the Veterans Health Administration

Year

Patients with any antipsychotics

LAI risperidone

Other LAI SGA

LAI paliperidone

Any LAI SGA

Any FGA LAI

Oral SGA

Oral FGA

N

%

N

N

%

N

%

N

N

N

2007

66,985

3625

5.4^

–-

–-

–-

3625

5.4^

5499

39,975

35,704

2008

68,565

3914

5.7^,#

–-

–-

–-

3914

5.7^,#

5361

41,773

35,372

2009

70,401

4258

6.0#

29

29

0.04^

4268

6.1^,#

5398

43,002

36,005

2010

71,250

4252

6.0^

512

511

0.7^,#

4487

6.3^,#

5237

43,335

36,637

2011*

71,842

4024

5.6

1346

1345

1.9

5036

7.0

5061

42,986

37,032

2012

72,230

3723

5.2^

1949

1944

2.7^

5431

7.5^

4855

42,617

36,976

2013

72,275

3541

4.9^,#

2585

2547

3.5^,#

5889

8.2^,#

4535

42,669

37,266

2014

71,959

3199

4.5^,#

3116

2914

4.1^,#

6075

8.4^,#

4133

43,226

35,889

2015

72,777

2838

3.9^,#

3991

3564

4.9^,#

6542

9.0^,#

4145

44,531

34,617

Change

5792

 − 787

 − 1.5%

3991

3564

4.9%

2917

3.6%

 − 1354

4556

 − 1087

%Change

8.6%

 − 21.7%

27.9%

–-

–-

–-

80.5%

66.1%

 − 24.6%

11.4%

 − 3.0%

  1. *Used as the reference year to define pre- and post-publication of a cooperative study (CSP#555)
  2. ^Statistically significant difference as compared to the reference year
  3. #Statistically significant difference when compared to the previous year (excluding comparisons with the reference year)