Table 4 Management of patients in the experimental group at day 5
Temperature | CRP | Treatment plan |
|---|---|---|
 < 38 °C |  ≤ 10 mg/L | Corticosteroid taper: oral prednisolone 1 mg/kg/day for 5 days, then 0·5 mg/kg/day for another 5 days, then stop; continue aspirin at 3–5 mg/kg/day for at least 21 days after resolution of fevera |
 < 38 °C |  > 10 mg/L | Continue oral prednisolone 2 mg/kg/day until afebrile AND CRP ≤ 10 mg/L (then taper as above) and consider rescue treatment at discretion of local investigator; continue aspirin at 3–5 mg/kg/day for at least 21 days after resolution of fevera |
 ≥ 38 °C |  ≤ 10 mg/L | Continue oral prednisolone 2 mg/kg/day until afebrile AND CRP ≤ 10 mg/L (then taper as above) and consider rescue treatment at discretion of local investigator; continue with aspirin at 40 mg/kg/day until afebrile |
 ≥ 38 °C |  > 10 mg/L | Continue oral prednisolone 2 mg/kg/day until afebrile AND CRP ≤ 10 mg/L (then taper as above) and consider rescue treatment at discretion of local investigator; continue with aspirin at 40 mg/kg/day until afebrile |