Temperature | CRP | Treatment plan |
---|---|---|
 < 38 °C |  ≤ 10 mg/L | No further treatment required [reassess on day 5]; reduce aspirin to 3–5 mg/kg/day when afebrile for at least 48 h and continue for at least 21 days after resolution of fevera |
 < 38 °C |  > 10 mg/L but ≤ 50% of baseline | No further treatment required [reassess on day 5]; reduce aspirin to 3–5 mg/kg/day when afebrile for at least 48 h and continue for at least 21 days after resolution of fevera |
 < 38 °C |  > 10 mg/L and still > 50% of baseline | Second dose of IVIG; reduce aspirin to 3–5 mg/kg/day when afebrile for at least 48 h and continue for at least 21 days after resolution of fevera |
 ≥ 38 °C |  ≤ 10 mg/L | Second dose of IVIG; continue with aspirin at 40 mg/kg/day until afebrile |
 ≥ 38 °C |  > 10 mg/L but ≤ 50% of baseline | Second dose of IVIG; continue with aspirin at 40 mg/kg/day until afebrile |
 ≥ 38 °C |  > 10 mg/L and still > 50% of baseline | Second dose of IVIG; continue with aspirin at 40 mg/kg/day until afebrile |