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Table 3 Patient demographics and baseline characteristics in AFM11-102

From: Safety of AFM11 in the treatment of patients with B-cell malignancies: findings from two phase 1 studies

 

Safety population

(n = 17)

Age (y), mean (SD)

46.8 (18.80)

Male, n (%)

7 (41.2)

Type of ALL, n (%)

 CD19 + B-precursor Philadelphia-chromosome negative ALL

16 (94.1)

 CD19 + B-precursor Philadelphia-chromosome positive ALL

1 (5.9)

Time since diagnosis (y), mean (SD)

1.62 (1.11)

Total number of relapses, mean (SD)

1.6 (0.70)

Previous treatments, n (%)

 Chemotherapy

17 (100)

 Targeted therapya

3 (17.6)

 Radiotherapy

3 (17.6)

 Peripheral blood stem cell transplant

5 (29.4)

Time from last treatment, n (%)

 < 1 month

6 (35.3)

 1 to < 3 months

4 (23.5)

 3 to < 6 months

1 (5.9)

 6 to < 12 months

2 (11.8)

 ≥ 12 months

4 (23.5)

  1. ALL acute lymphoblastic leukaemia; SD standard deviation
  2. aTargeted therapy included velcade asparaginase, imatinib ponatinib or rituximab