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Table 4 Confidence in overall quality and reflection of different stakeholder’s views by method group (Likert scale from 1, completely unconfident, to 7, completely confident)

From: How do we know a treatment is good enough? A survey of non-inferiority trials

Method group

Opinion seeking without evidence base (N = 7)a

Evidence base without opinion seek (N = 11)a

Opinion seeking and evidence based (N = 17)a

Neither opinion seek nor evidence base (N = 6)b

 

Mean (SD)

Median (P25–P75)

Mean (SD)

Median (P25–P75)

Mean (SD)

Median (P25–P75)

Mean (SD)

Median (P25–P75)

Confidence in overall quality

3.9 (1.9)

4.0 (2.0–6.0)

5.1 (1.4)

5.0 (4.0–6.0)

4.8 (1.1)

5.0 (4.0–5.0)

5.2 (2.3)

6.0 (4.0–7.0)

Margin reflects patient’s views

2.7 (2.1)

2.0 (1.0–5.0)

2.8 (1.7)

3.0 (1.0–4.0)

4.1 (1.4)

4.0 (3.0–5.0)

4.2 (1.9)

4.5 (3.0–6.0)

Margin reflects clinician’s views

5.6 (1.3)

6.0 (5.0–6.0)

5.3 (1.1)

5.0 (4.0–6.0)

5.5 (1.3)

6.0 (5.0–6.0)

5.7 (1.0)

6.0 (5.0–6.0)

Margin reflects policy maker’s views

2.7 (1.6)

2.0 (1.0–4.0)

4.4 (1.7)

4.0 (4.0–5.0)

4.0 (1.3)

4.0 (4.0–5.0)

5.2 (1.2)

5.0 (4.0–6.0)

Considered the method appropriate—n (%)

4 (57.1)

9 (81.8)

15 (88.2)

5 (83.3)

  1. SD, standard deviation; P25, percentile 25th; P75, percentile 75th
  2. aMethods were used with or without other methods (e.g. feasibility and margin recommendation)
  3. bOther methods are feasibility and margin recommendation