Effect of early stellate ganglion block in cerebral vasospasm after aneurysmal subarachnoid hemorrhage (BLOCK-CVS): study protocol for a randomized controlled trial

Table 1 SPIRIT flow diagram

Time point (from onset)	Operation			Post-operation follow-up
	Pre	Dur	Aft	Day	Day	Day	Discharge	Day 30 or
	Day 1–2			2–6	7–10	10–14		Day 90
Enrollment
Eligibility screen	✖
Recruitment	✖
Consent	✖
Randomization and allocation	✖
Interventions
SGB	✖
Camouflage action (non-SGB)	✖
Block-related information	✖
Assessments
Baseline variables	✖
Neurological examination	✖		✖	✖	✖	✖	✖
Physiological parameters	✖	✖	✖	✖	✖	✖	✖
MMSE	✖		✖		✖		✖	✖
CAM-ICU	✖		✖	✖
mRS							✖	✖
TCD	✖		✖	✖	✖	✖
CT	✖		✖		✖		✖
CTA/CTP	✖				✖
Complications		✖	✖	✖	✖	✖	✖	✖
All adverse events		✖	✖	✖	✖	✖
Length of stay							✖
All-cause mortality							✖	✖

SGB Stellate ganglion block, TCD Transcranial Doppler, MMSE Mini-Mental State Examination, CAM-ICU Confusion Assessment Method for the Intensive Care Unit, mRS modified Rankin scale, CT Computed tomography, CTA Computed tomography angiography, CTP Computed tomography perfusion imaging

ISSN: 1745-6215