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Table 2 Schedule of enrollment, interventions, and assessments

From: Infraslow closed-loop brain training for anxiety and depression (ISAD): a protocol for a randomized, double-blind, sham-controlled pilot trial in adult females with internalizing disorders

 

T0

T1

T2

Allocation

T3-8

T9

T10-15

T16

T17

Enrollment

 Eligibility screen (MINI)

✓

        

 Informed consent

✓

        

 Anthropometric measures

✓

        

Assessments

 PROs

 

✓

✓

  

✓

 

✓

✓

 EEG

 

✓

✓

  

✓

 

✓

✓

 ECG

 

✓

✓

  

✓

 

✓

✓

 DESS

    

✓

 

✓

✓

✓

 Blinding integrity

     

✓

   

Groups

 Active

✓

✓

✓

✓

✓

✓

✓

✓

✓

 Sham

✓

✓

✓

✓

✓

✓

   
  1. Abbreviations: MINI Miniature International Neuropsychiatric Interview, PROs patient-reported outcomes, EEG electroencephalography, ECG electrocardiography, T0 interview, T1 baseline #1, T2 baseline #2, T3–8 neurofeedback sessions 1 through 6, T9 post 6th session assessments, T10–15 neurofeedback sessions 7 through 12, T16 post 12th session assessments, T17 1-month follow-up assessments