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Table 2 Example vaccine uptake app components and HBM domains/vaccine hesitancy issues addressed

From: Improving pediatric COVID-19 vaccine uptake using an mHealth tool (MoVeUp): study protocol for a randomized, controlled trial

Vaccine Uptake App Component

Example Componenta

HBM domain

NIH CEAL Known Barrier/Concern

Push Notifications, to include:

-Behavioral nudges

-Alerts to information about the vaccine in general

-Clinic-specific information on vaccine issues

“Your child’s COVID-19 vaccine is available at [insert clinic name]. To schedule your appointment, touch here.” Links to local clinic’s appointment making resource

“Did you know that over xx million children have received the COVID-19 vaccine? Hear from parents why they chose to vaccinate their children.” (Links to Vignette)

“More than xx children have received the vaccine at your clinic. Click here to schedule your child’s vaccine appointment today.”

“[Organization] is providing free rides to [insert vaccination site]. Click here for more information.”

“COVID cases in children in your area are increasing. Protect your child with the vaccine today. Click here to schedule your appointment.”

Perceived barriers to vaccination

Cues to action

Psychological characteristics

(peer group pressure)

Perceived benefits

Susceptibility to disease

Access issues/questions

Do I need to pay for a COVID-19 vaccine?

Vaccine Access Pathway (“Find your child’s COVID-19 vaccine”)

Information about local events for vaccination; information about free rides to a vaccination site; links to schedule vaccine visits

Perceived barriers to vaccination

Cues to action

Access to care

Psychological characteristics

Do I need an ID to get COVID-19 vaccine for my child?

Do I (my child) have to be a legal resident to get COVID-19 vaccine?

Do I need proof of insurance to get the COVID-19 vaccine for my child?

Do I need to provide personal identifying information (address, phone number, etc.) to get my child vaccinated?

Vignettes/step-wise decision support. Will include:

-Relatable storytelling

-Testimonials from local staff/leaders

Vignette: Taking your teenager to get vaccinated

Vignette: Why I vaccinated my child

Vignette: Parent of child with COVID-19/MISC. Their story

Vignette: Provider testimonial (trusted messenger) on long COVID/MISC and the choice to vaccinate their own children

Vignette: School outbreak, from the perspective of teachers/students/parents

Vignette: Student athlete who got COVID

Vignette: Protecting a vulnerable family member

Health motivation

Safety/perceived severity of effects from the vaccine

Psychological characteristics

Perceived benefits

Perceived susceptibility

Perceived susceptibility

Perceived severity of SARS-CoV-2

Psychological characteristics

Perceived susceptibility

Perceived severity of SARS-CoV-2

Perceived benefits of the vaccine

Health motivation

Cues to action

Perceived susceptibility

Perceived severity of SARS-CoV-2

Perceived benefits of the vaccine

Cues to action

Perceived susceptibility

Perceived severity of SARS-CoV-2

Perceived benefits of the vaccine

Psychological characteristics

Perceived benefits of the vaccine

Health motivation

Cues to action

Does the COVID-19 vaccine impact fertility?

How effective is the COVID-19 vaccine?

Does COVID-19 cause disease in children? Is it worse than the flu?

Are COVID-19 vaccines safe?

How were COVID-19 vaccines developed?

Does COVID-19 infect children aren’t they too healthy to get sick?

Is natural immunity just as good as getting vaccinated?

Does receiving the vaccine give you COVID-19?

If you are vaccinated, then why do I have to get vaccinated?

Customization for clinic site

Clinic logos/colors

Clinic location/contact information

Links to clinic’s website and appointment-making tools

Clinic-specific vaccination events (when applicable)

Perceived barriers to vaccination

Psychological characteristics

Cues to action (trusted organization)

Health motivation (trusted organization)

Questions around trust and trusted messengers

Customization for participant socio-demographics

Vignette pictures/content adjusted for race, ethnicity, language, and/or rurality

Psychological characteristics

Susceptibility to disease

Benefits of vaccination

Health motivation

Does the vaccine work for people like my child?

Has the vaccine been tested in people like my child?

Self-directed learning pathways

COVID-19 by the numbers (stats and pictographs)

Natural immunity vs vaccination

Frequently asked questions about COVID-19

Susceptibility/severity of infection

Benefits of vaccination

Benefits of vaccination

Susceptibility/severity of infection

Potentially multiple avenues, depending upon user motivation to access information

Various questions, concerns, and misinformation topics, with focus on topics from CEAL, CDC, and qualitative interviews

  1. HBM Health belief model
  2. aSpecific content may vary based on user acceptance testing and qualitative study results