Table 2 Estimated effect size for neurodevelopmental outcome (survival at 2 years without moderate/severe neurodevelopmental impairment) for anticipated questionnaire returns
Size per group | Survival without moderate/severe neurodevelopmental impairment | Detectable effect size |
|---|---|---|
Power 0.8, alpha 0.05, initial incidence of survival without moderate/severe neurodevelopmental impairment of 50% | ||
350 | 60.7% | 10.7% |
300 | 61.6% | 11.6% |
250 | 62.7% | 12.7% |
200 | 64.4% | 14.6% |
Power 0.9, alpha 0.05, initial incidence of survival without moderate/severe neurodevelopmental impairment of 50% | ||
350 | 62.3% | 12.3% |
300 | 63.3% | 12.3% |
250 | 64.6% | 14.6% |
200 | 66.4% | 16.4% |