Table 1 Presents all outcome variables, data collection instruments, measures, time points and statistical analysis

Primary outcome

 1. Change in shoulder pain and function

SPADI (questionnaire)

Score 0–100 (continuous)

0, 4, 8 and 12 weeks

Repeated-Measures, Mixed Effects Model

Key secondary outcomes

 1. Change in shoulder pain

SPADI (questionnaire)

Score 0–10 (continuous)

0, 4, 8 and 12 weeks

Repeated-Measures, Mixed Effects Model

 2. Change in shoulder function

SPADI (questionnaire)

Score 0–10 (continuous)

0, 4, 8 and 12 weeks

Repeated-Measures, Mixed Effects Model

 3. Clinical response

SPADI minimal important change criteria^a—no. (%)

SPADI change score (dichotomous)

12 weeks (follow-up)

Logistic regression after 12 weeks

 4. Impression of the treatment´s success

GPE (questionnaire)

Score 0–7 (continuous)

4, 8 and 12 weeks

Repeated-Measures, Mixed Effects Model

 5. and 6. Change in A- and P-ROM in the affected shoulder

Smartphone Inclinometer test protocol

Degree (continuous)

0 and 12 weeks

ANCOVA

 7. Number of treatments received due to shoulder symptoms^b

Questionnaire

Mean number of received treatments (continuous)

12 weeks (follow-up)

ANCOVA

 8. Change in maximum shoulder pain intensity within the previous 24 h in the affected shoulder

NRS in questionnaire

Score 0–10 (continuous)

0, 4, 8 and 12 weeks

Repeated-Measures, Mixed Effects Model

 9. Change in shoulder pain during general activities within the previous 24 h in the affected shoulder

NRS in questionnaire

Score 0–10 (continuous)

0, 4, 8 and 12 weeks

Repeated-Measures, Mixed Effects Model

 10. Change in shoulder pain at rest within the previous 24 h in the affected shoulder

NRS in questionnaire

Score 0–10 (continuous)

0, 4, 8 and 12 weeks

Repeated-Measures, Mixed Effects Model

 11. Change in shoulder pain during sleep within the previous 24 h in the affected shoulder

NRS in questionnaire

Score 0–10 (continuous)

0, 4, 8 and 12 weeks

Repeated-Measures, Mixed Effects Model

 12. Change in shoulder pain during flexion/rotation/abduction in the affected shoulder

NRS / test protocol

Score 0–10 (continuous)

0 and 12 weeks

ANCOVA

Other exploratory outcomes

 1. Pain medication consumption

Questionnaire

Type (categorical)

0, 4, 8 and 12 weeks

Logistic regression

 2. Depression score

PHQ-9 (questionnaire)

Score 0–27 (continuous)

0, 4, 8 and 12 weeks

ANCOVA

 3. Anxiety score

GAD-7 (questionnaire)

Score 0–21(continuous)

0, 4, 8 and 12 weeks

ANCOVA

Sensitivity analyses

 Per-protocol analysis^c

ANCOVA

 As-treated analysis^c

ANCOVA