Table 1 Baseline characteristics of included trials
From: Access to unpublished protocols and statistical analysis plans of randomised trials
Characteristic | High impact cohort (n = 11) | PubMed cohort (n = 85) | Total (n = 96) |
|---|---|---|---|
Any for profit funding | |||
Yes | 4 (36) | 10 (12) | 14 (15) |
No | 7 (64) | 44 (52) | 51 (53) |
Unclear | 0 (0) | 31 (36) | 31 (32) |
Type of intervention | |||
Pharmacologic | 5 (45) | 39 (46) | 44 (46) |
Surgical | 1 (9) | 8 (9) | 9 (9) |
Psychosocial/behavioural/educational | 0 (0) | 11 (13) | 11 (11) |
Other | 4 (36) | 26 (31) | 30 (31) |
Multiple types | 1 (9) | 1 (1) | 2 (2) |
Cluster trial | 1 (9) | 2 (2) | 3 (3) |
Factorial trial | 1 (9) | 0 (0) | 1 (1) |
Crossover trial | 0 (0) | 3 (4) | 3 (3) |
Non-inferiority trial | 4 (36) | 4 (5) | 8 (8) |
No. of treatment arms | |||
Two | 9 (82) | 69 (81) | 78 (81) |
Three or more | 2 (18) | 16 (19) | 18 (19) |
Sample size | |||
Median, IQR | 450 (300, 1499) | 93 (60, 168) | 101 (61, 208) |