Table 1 Outcome Taxonomy adapted from Dodd et al. [28]

Outcome taxonomy

 1. Mortality

 2. 2–24: Physiological/clinical

 2: Blood and lymphatic system outcomes

 3: Cardiac outcomes

 4: Congenital, familial and genetic outcomes

 5: Endocrine outcomes

 6: Ear and labyrinth outcomes

 7: Eye outcomes

 8: Gastrointestinal outcomes

 9: General outcomes

 10: Hepatobiliary outcomes

 11: Immune system outcomes

 12: Infection and infestation outcomes

 13: Injury and poisoning outcomes

 14: Metabolism and nutrition outcomes

 15: Musculoskeletal and connective tissue outcomes

 16: Outcomes relating to neoplasms: benign, malignant and unspecified

 17: Nervous system outcomes

 18: Pregnancy, puerperium and perinatal outcomes

 19: Renal and urinary outcomes

 20: Reproductive system and breast outcomes

 21: Psychiatric outcomes

 22: Respiratory, thoracic and mediastinal outcomes

 23: Skin and subcutaneous tissue outcomes

 24: Vascular outcomes

Functioning

 25: Physical functioning

 26: Social functioning

 27: Role functioning

 28: Emotional functioning/well-being

 29: Cognitive functioning

 31: Perceived health status

 32: Delivery of care, including;

  - Satisfaction/patient preference

  - Acceptability and availability

  - Adherence/compliance

  - Withdrawal from treatment

  - Appropriateness of treatment

  - Process, implementation, and service outcomes

 33: Personal circumstances

Resource use

 34: Economic

 35: Hospital

 36: Need for further intervention

 37: Societal/carer burden

 38: Adverse events/effects