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Table 1 Severity-based criteria of diagnosis of CLD at 36 weeks’ PMA

From: AZTEC—azithromycin therapy for prevention of chronic lung disease of prematurity: a statistical analysis plan for clinical outcomes

Received respiratory support and/or supplementary oxygen for more than 28 days, cumulatively, and the following:

Mild CLD

• Breathing room air

Moderate CLD

• Require < 30% oxygen (or low flow 0.01–1.0 L/ min), not receiving any respiratory support

Severe CLD

• Require ≥ 30% oxygen (or low flow ≥ 1.1 L/min), still receiving respiratory support (ventilation, continuous positive airway pressure [CPAP], high flow oxygen)