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Table 4 Percent (%) missing responsesa, by data element and trial start year

From: Update on the clinical trial landscape: analysis of ClinicalTrials.gov registration data, 2000–2020

Year

Facilities (%)

Randomized (%)

Masked (%)

Tx groups (%)

Primary purpose (%)

Intervention model (%)

Eligibility: sex (%)

2000

17.4

21.5

22.5

55.6

2.6

25.8

0.5

2001

16.6

13.6

14.3

51.0

3.0

18.5

0.6

2002

17.0

7.7

6.7

49.0

5.8

10.0

0.2

2003

14.4

4.9

3.6

44.0

5.0

6.7

0.2

2004

14.0

4.0

3.4

42.8

5.0

5.3

0.2

2005

11.4

2.7

2.0

36.8

5.2

3.2

0.1

2006

9.3

1.7

1.7

27.0

4.0

2.2

0.1

2007

8.6

1.4

1.5

13.6

3.7

1.6

0.1

2008

8.3

1.2

1.0

5.8

4.3

1.2

0.1

2009

7.8

0.8

0.5

4.7

4.5

0.9

0.1

2010

7.3

0.6

0.4

3.3

4.4

0.6

0.1

2011

7.2

0.7

0.4

2.6

4.9

0.4

0.1

2012

7.9

0.5

0.4

1.3

4.2

0.4

0.1

2013

8.5

0.5

0.3

0.5

3.7

0.3

0.1

2014

10.8

0.3

0.3

0.4

3.5

0.3

0.1

2015

13.5

0.3

0.3

0.3

2.4

0.2

0.1

2016

14.9

0.3

0.4

0.3

1.1

0.2

0.1

2017

5.4

0.3

0.0

0.5

0.1

0.0

0.0

2018

4.9

0.3

0.0

0.5

0.0

0.0

0.1

2019

6.3

0.3

0.0

0.5

0.0

0.0

0.0

2020

7.6

0.1

0.0

0.6

0.0

0.0

0.0

  1. a Null or missing values for selected required data elements