Table 3 Completion status, enrollment, and result reporting among completed registered trials, 2000–2020
From: Update on the clinical trial landscape: analysis of ClinicalTrials.gov registration data, 2000–2020
Year started | Completed | Time to completion | Sample sizea | Sample size categories (%) | Reported results | Time to report resultsd | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|
N | Years (median, IQR) | (Median, IQR) | 01–50 | 50–100 | 101–500 | 500–1000 | >1000 | Yes N (%) | <12 mos. N (%) | Months Median (IQR) | |
2000 | 1572 | 4.3 (2.3, 6.8) | 82 (33, 256) | 38.3 | 17.6 | 28.8 | 8.3 | 7 | 137 (8.7) | 0 (0) | 49 (20, 87) |
2001 | 2038 | 3.9 (2.0, 6.3) | 91 (37, 270) | 34.6 | 19.6 | 30.6 | 7.8 | 7.4 | 207 (10.2) | 0 (0) | 55 (27, 97) |
2002 | 3000 | 3.4 (1.5, 5.5) | 82 (36, 257) | 37.8 | 18.9 | 31.7 | 7.3 | 4.3 | 359 (12.0) | 0 (0) | 57 (22, 84) |
2003 | 4062 | 3.3 (1.7, 5.1) | 81 (36, 251) | 34.6 | 20.2 | 31.8 | 7.7 | 5.6 | 650 (16.0) | 0 (0) | 53 (23, 79) |
2004 | 5261 | 2.9 (1.5, 4.6) | 75 (33, 242) | 37.7 | 19.0 | 31.9 | 7.8 | 5.2 | 1000 (19.0) | 0 (0) | 47 (21, 72) |
2005 | 6240 | 2.6 (1.4, 4.3) | 69 (30, 200) | 39.2 | 19.2 | 30.8 | 6.3 | 4.5 | 1526 (24.5) | 0 (0) | 39 (19, 69) |
2006 | 7221 | 2.3 (1.3, 3.9) | 62 (29, 200) | 38.4 | 18.9 | 30.7 | 6.8 | 5.2 | 2296 (31.8) | 0 (0) | 32 (14, 61) |
2007b | 7888 | 2.0 (1.0, 3.7) | 60 (25, 168) | 40.3 | 20.6 | 28.5 | 5.9 | 4.7 | 2840 (36.0) | 0 (0) | 29 (13, 56) |
2008 | 8926 | 1.9 (0.8, 3.5) | 58 (24, 150) | 42.2 | 20.1 | 29.0 | 5.0 | 3.7 | 3165 (35.5) | 9 (0.1) | 27 (12, 52) |
2009 | 9605 | 1.9 (0.9, 3.4) | 58 (24, 150) | 42.6 | 20.7 | 28.1 | 4.8 | 3.8 | 3322 (34.6) | 16 (0.2) | 22 (12, 44) |
2010 | 9860 | 1.9 (0.8, 3.4) | 57 (24, 149) | 43.7 | 20.2 | 27.7 | 4.9 | 3.6 | 3136 (31.8) | 20 (0.2) | 19 (12, 39) |
2011 | 10,320 | 1.8 (0.8, 3.2) | 60 (25, 150) | 43.1 | 20.7 | 27.6 | 4.8 | 3.8 | 3135 (30.4) | 27 (0.3) | 18 (11, 35) |
2012 | 10,683 | 1.9 (0.9, 3.3) | 59 (24, 150) | 43.6 | 21.1 | 27.1 | 4.4 | 3.7 | 3069 (28.7) | 18 (0.2) | 15 (11, 30) |
2013 | 10,974 | 1.8 (0.8, 3.2) | 56 (24, 140) | 45.7 | 21.2 | 25.9 | 4.0 | 3.2 | 3192 (29.1) | 51 (0.5) | 14 (11, 27) |
2014 | 11,744 | 1.7 (0.8, 3.0) | 57 (24, 140) | 46.0 | 21.1 | 25.7 | 3.7 | 3.5 | 3107 (26.5) | 51 (0.4) | 13 (11, 24) |
2015c | 11,917 | 1.6 (0.8, 2.8) | 60 (25, 140) | 45.2 | 21.9 | 25.8 | 3.9 | 3.3 | 3034 (25.5) | 57 (0.5) | 12 (11, 22) |
2016 | 11,720 | 1.5 (0.8, 2.7) | 59 (24, 138) | 46.4 | 22.0 | 24.5 | 3.6 | 3.5 | 2635 (22.5) | 41 (0.3) | 12 (11, 20) |
2017 | 11,144 | 1.3 (0.7, 2.3) | 60 (26, 138) | 47.0 | 23.1 | 23.7 | 3.0 | 3.3 | 2268 (20.4) | 14 (0.1) | 12 (11, 18) |
2018 | 10,118 | 1.1 (0.5, 1.9) | 60 (26, 138) | 49.7 | 22.8 | 22.0 | 2.9 | 2.6 | 1643 (16.2) | 30 (0.3) | 12 (10, 16) |
2019 | 7925 | 0.8 (0.4, 1.5) | 60 (28, 130) | 52.7 | 24.0 | 19.0 | 2.1 | 2.2 | 862 (10.9) | 53 (0.7) | 11 (9, 13) |
2020 | 5282 | 0.6 (0.3, 1.0) | 62 (30, 150) | 49.6 | 23.5 | 21.1 | 2.5 | 3.3 | 358 (6.8) | 75 (1.4) | 10 (6, 12) |