The APPLE Tree programme: Active Prevention in People at risk of dementia through Lifestyle, bEhaviour change and Technology to build REsiliEnce—randomised controlled trial

Table 1 Participant timeline

	Enrolment	Baseline
TIMEPOINT	−t₁	0	s₁	s₂	s₃	s₄	s₅	s₆	s₇	s₈	s₉	s ₁₀	6M	12M	24M
ENROLMENT:
Eligibility screening	X
Informed consent		X
Randomisation		X
INTERVENTION:
Sessions 1–10			X	X	X	X	X	X	X	X	X	X
ASSESSMENTS:
Demographics		X
NTB		X												x	X
CSRI		X												X	X
EQ-5D-5L		X												X	X
FAQ		X												X	X
PSQI		X												X	X
HADS		X												x	X
MDS		X											X	X	X
24-h food recall		X												X	X
AUDIT		X												X	X
Smoking status		X												X	X
PSNS, LTE, BLS		X												X	X
GHQ-12		X												X	X
PM		X												X	X
PA		X												X	X
Bloods and saliva		X												X	X
Qualitative interviews (intervention arm)													X	X

Legend: AUDIT Alcohol Use Disorders Identification Tool, BLS brief loneliness scale, CSRI Client Service Receipt Inventory, EQ-5D-5L EuroQoL EQ-5D 5 Level, FAQ Functional Assessment Questionnaire, GHQ-12 General Health Questionnaire-12, HADS Hospital Anxiety and Depression Scale, LTE list of threatening experiences, MDS Mediterranean Diet Score, NTB Neuropsychological Test Battery, PSQI Pittsburgh Sleep Quality Index, PA physical activity (step count) and resting heart rate (over 2 weeks), PM physiological measures (gait speed, grip strength, weight, body mass index, and hip and waist circumference), PSNS primary support network size

ISSN: 1745-6215