Table 3 Overview of all measurements in the EFFECT trial

 Cancer-related fatigue

EORTC QLQ-FA12

X

X

X

X

 Health-related quality of life

EORTC QLQ-C30

X

X

X

X

  Breast cancer-specific symptoms

EORTC QLQ-BR45

X

X

X

X

  Depression and anxiety

Patient Health Questionnaire (PHQ-4)

X

X

X

X

  Sleep problems

Pittsburgh Sleep Quality Index (PSQI)

X

X

X

X

  Pain

Brief Pain Inventory Short Form (BPI-SF), PainDETECT, Pain Catastrophizing Scale (PCS)

X

X

X

X

  Quality of working life^a

Quality of Working Life Questionnaire for Cancer Survivors (QWLQ-CS)

X

X

X

X

  Subjectively measured physical activity

Modified version of the GODIN questionnaire

X

X

X

X

  Productivity loss

Productivity Cost Questionnaire (iPCQ)

X

X

X

  Healthcare resources consumption

Medical Consumption Questionnaire (iMCQ)

X

X

X

  Health-related quality of life

EQ-5D-5L

X

X

X

X

  Urinary incontinence

International Consultation on Incontinence Questionnaire -Urinary Incontinence Short Form (ICIQ-UI SF)^b

X

X

X

X

  Satisfaction with exercise intervention^g

Self-developed questionnaire

X

X

X

  Physical performance

5-times sit-to-stand, short Fullerton Advanced Balance (S-FAB) scale

X

X

X

  Physical fitness

Steep Ramp Test (SRT), endurance cycle test, handgrip- and leg strength test, Cardiopulmonary Exercise Testing (CPET)^c, Isokinetic and isometric peak torque^d

X

X

X

  Objectively measured physical activity

Physical activity tracker (Fitbit Inspire HR)

X

X

X

X

  Muscle thickness^e

Ultrasonography

X

X

X

  Body composition

Bio-impedance, DEXA^f

X

X

X

  Anthropometry

• Body weight

X

X

X

• Waist and hip circumference

X

X

X

• Height

X

  Resting heart rate and blood pressure

-

X

X

X

  Blood markers

Plasma, serum, buffy coat and peripheral blood mononuclear cells

X

X

X

 Socio-demographic data

Self-developed questionnaire

X

 Medical history and concomitant diseases

Medical records

X

X

X

X

 Cancer progress and treatment over the course of the study

Medical records

X

X

X

X

 Cancer characteristics and treatment history

Medical records

X

X

X

X

 Concomitant medication

Medical records

X

X

X

X

 Adverse events

Reports of patients, trainers, oncology nurses, physicians or medical records

X

X

X

X

 Overall and breast-cancer-specific survival and progression-free survival

Medical records and/or cancer registry