Skip to main content

Table 2 Parameters and assessment time points

From: AMAZONE: prevention of persistent pain after breast cancer treatment by online cognitive behavioral therapy—study protocol of a randomized controlled multicenter trial

Parameters

Instrument

T 0

T1

T2

T3

T4

Pain operated breast

NRS

x

x

x

x

x

Pain localization

x

 

x

x

x

BPI [60]

x

 

x

x

x

 

DN4 [59]

x

x

x

x

x

Pain unrelated to BC treatment elsewhere

NRS

x

 

x

x

x

Localization

x

 

x

x

x

Shoulder function

DASH [63]

x

  

x

x

Pain sensitivity

CPM

x

x

 

x

 

QST

x

  

x

 

Pain catastrophizing

PCS [54]

x

 

x

x

x

Anxiety

HADS-A [52]

x

 

x

x

x

Depression

PROMIS short form v1.0 [64, 65]

x

 

x

x

x

Quality of life

EORTC-QLQ C30+BC [66]

x

  

x

x

Surgical fear

SFQ [67] & single item [16]

x

    

Fear of recurrence

CARS [68]

x

 

x

x

x

Breast cancer characteristics

TNM, receptors, histological profile

x

  

x

 
 

non-related chronic pain complaints

x

  

x

x

 

pain medication

x

x

x

x

x

 

Sedative and antidepressive medication

x

x

x

x

x

Patient characteristics

BMI

x

  

x

x

 

Comorbidity and intoxications

x

   

x

 

Unspecific symptoms

x

 

x

x

x

Breast cancer treatment details

Type of surgery

 

x

x

x

x

ICBN handling

 

x

   

Breast cancer treatment complications

 

x

x

x

x

Radiotherapy

  

x

x

x

Chemotherapy

x

 

x

x

x

Hormonal therapy

x

 

x

x

x

Anesthesia

Perioperative regional techniques

 

x

   

Acute pain day 0–7

 

x

   

Patient compliance with protocol

   

x

  
  1. T0 1–3 weeks pre-surgery, T1 postoperative week, T2 2 months follow-up, T3 6 months follow-up, T4 12 months follow-up. NRS numerical rating scale (0=no pain, 10=maximum pain), BPI brief pain inventory, DN4 doleur neuropathique 4 questions, CPM conditioned pain modulation, QST quantitative sensory testing, PCS pain catastrophizing scale, HADS hospital anxiety and depression scale, PROMIS patient-reported outcomes measurement information system, EORTC-QLQ European Organization for Research and Treatment of Cancer Quality of Life Questionnaire, SFQ surgical fear questionnaire, CARS fear of cancer recurrence scale, DASH disability of the arm, shoulder and hand questionnaire, BMI body mass index, ICBN intercostobrachial nerve