Povidone-Iodine | Chlorhexidine | |
---|---|---|
Participant characteristics | (n = XXX) | (n = XXX) |
Age, years, mean (SD) | ||
Sex, n (%) | ||
Male | ||
Body mass index, kg/m2, n (%) | ||
Underweight (BMI < 18.5) | ||
Normal weight (18.5–24.9) | ||
Overweight (25–29.9) | ||
Obese (BMI > 30) | ||
Diabetes, n (%) | ||
Current smoker, n (%) | ||
Injury severity score, median (IQR) | ||
American Society of Anesthesiologists Physical Score, n (%) | ||
Class I or II | ||
Class III or higher | ||
Fracture characteristics† | (n = XXX) | (n = XXX) |
Severity of open fracture, n (%) | ||
Gustilo-Anderson type I/II | ||
Gustilo-Anderson type IIIA | ||
Gustilo-Anderson type IIIB/IIC | ||
Location of fracture, n (%) | ||
Lower extremity or pelvis | ||
Upper extremity | ||
Wound contamination, n (%) | ||
None or minimal contamination | ||
Surface contamination | ||
Contaminant embedded in bone or deep soft tissue | ||
Fracture management† | (n = XXX) | (n = XXX) |
Temporary fracture stabilization, n (%) | ||
Number of planned surgeries, n (%) | ||
1 | ||
2 | ||
3 or more | ||
Preoperative antiseptic bathing with chlorhexidine gluconate*, n (%) | ||
Method of definitive fracture management, n (%) | ||
Plate and screw fixation | ||
Intramedullary nail | ||
External fixation | ||
Other | ||
Intraoperative topical antibiotics*, n (%) | ||
Skin closure method**, n (%) | ||
Primary wound closure | ||
Skin graft | ||
Local flap | ||
Free flap | ||
No closure attempted/secondary wound healing |